4-Fluoro-3-nitroaniline
4-Fluoro-3-nitroaniline (CAS: 364-76-1), with the molecular formula FC6H3(NO2)NH2 and a molecular weight of 156.11 g/mol, is a key fluorinated organic building block. It is an aniline derivative characterized by the presence of both a fluorine atom and a nitro group on the aromatic ring. This compound serves as a valuable intermediate in the synthesis of complex organic molecules, finding utility in various chemical research and development applications.

Preparation of Hair Dyes
4-Fluoro-3-nitroaniline has been documented for its use in the preparation of commercial hair dye formulations. Its specific chemical structure allows for incorporation into colourant systems, contributing to the final hue and performance of the dye.
Organic Synthesis Intermediate
As a functionalized aromatic amine, this compound is a versatile building block in organic synthesis. The fluorine and nitro substituents offer distinct reactivity, enabling its use in the creation of novel chemical entities for research and development.
Fluorinated Building Block
This chemical acts as a useful fluorinated building block for introducing fluorine into more complex molecular structures. Compounds containing fluorine often exhibit unique physicochemical properties, making them of interest in pharmaceuticals and materials science.
| Molecular weight | 156.11 |
|---|---|
| Linear formula | FC6H3(NO2)NH2 |
| Assay | 97% |
| Application | 4-Fluoro-3-nitroaniline was used in the preparation of commercial hair dyes1. |
| Melting point | 94-96 °C(lit.) |


Hazard statements
- H228Flammable solid
- H302Harmful if swallowed
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 91 °C / 195.8 °F |
| Transport (UN / ADR) | UN 1325 4.1 / PGII |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22 |
| Safety statements (S) | 36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Fluoro-3-nitroaniline used for?
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4-Fluoro-3-nitroaniline is used as an intermediate in organic synthesis, particularly noted for its application in the preparation of hair dyes and as a fluorinated building block.
What are the CAS number and formula for 4-Fluoro-3-nitroaniline?
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The CAS number for 4-Fluoro-3-nitroaniline is 364-76-1, and its molecular formula is FC6H3(NO2)NH2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Fluoro-3-nitroaniline with an assay of 97%. We do not represent this product as USP, BP, or EP grade; it is supplied for research and laboratory use.
How should 4-Fluoro-3-nitroaniline be handled safely?
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4-Fluoro-3-nitroaniline is classified as Danger, with hazards including flammability (H228) and harmful if swallowed (H302). Appropriate personal protective equipment such as a dust mask (type N95), eyeshields, and gloves should be worn. Handle in a well-ventilated area away from ignition sources.
How is 4-Fluoro-3-nitroaniline packed and exported?
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As a flammable solid (UN 1325, 4.1/PGII), 4-Fluoro-3-nitroaniline is carefully packed and exported by Tech Serve Solutions in compliance with international shipping regulations for hazardous materials.
How can I request a quote or sample for 4-Fluoro-3-nitroaniline?
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To request a quote or a sample of 4-Fluoro-3-nitroaniline, please contact our sales team through the website or by phone, providing your contact details and desired quantity.
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