Diethyl 2-bromoethylphosphonate
Diethyl 2-bromoethylphosphonate (CAS 5324-30-1) is a valuable organophosphorus compound with the linear formula BrCH2CH2P(O)(OCH2CH3)2 and a molecular weight of 245.05 g/mol. It serves as a key reactant in diverse chemical synthesis applications, including C-C bond formation, Horner-Wadsworth-Emmons olefination reactions, and the creation of specialized materials like organosoluble zirconium phosphonate nanocomposites. Its utility extends to radical coupling and the synthesis of dental adhesives.
- IUPAC
- (2-Bromoethyl)phosphonic acid diethyl ester,NSC 119421,NSC 2672
Chemical Synthesis and C-C Bond Formation
This phosphonate ester is employed in various synthetic strategies, including radical coupling reactions and the formation of new carbon-carbon bonds. Its structure makes it suitable for complex organic transformations.
Horner-Wadsworth-Emmons Reagent
As a component in Horner-Wadsworth-Emmons olefination reactions, it facilitates the synthesis of alkenes. This is a crucial method for constructing unsaturated organic molecules.
Material Science Applications
It acts as a reactant in the synthesis of organosoluble zirconium phosphonate nanocomposites, contributing to the development of advanced materials with specific properties.
Asymmetric Epoxidation
The compound is utilized in the asymmetric epoxidation of unfunctionalized olefins, a stereoselective process vital for creating chiral building blocks in organic chemistry.
Dental Adhesives
It is used in the synthesis of hydrolytically stable phosphonic acids, which are developed for applications as effective dental adhesives, highlighting its biomedical relevance.
| Molecular weight | 245.05 |
|---|---|
| Linear formula | BrCH2CH2P(O)(OCH2CH3)2 |
| Assay | 97% |
| Boiling point | 75 °C/1 mmHg(lit.) |
| Density | 1.348 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.461(lit.) |
| Application | Reactant involved in:• Radical coupling1• Synthesis of organosoluble zirconium phosphonate nanocomposites2• Click-chemistry3• Asymmetric epoxidation of unfunctionalized olefins4• Negishi alkyl-aryl cross-coupling5• Synthesis of hydrolytically stable phosphonic acids for use as dental adhesives6 |
| Protective equipment | Eyeshields, Gloves, half-mask respirator (EU), half-mask respirator (US), multi-purpose combination respirator cartridge (US) |
|---|---|
| Flash point | 110 °C / 230 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Diethyl 2-bromoethylphosphonate used for?
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Diethyl 2-bromoethylphosphonate is used as a reactant in chemical synthesis, including radical coupling, Horner-Wadsworth-Emmons olefination, click-chemistry, asymmetric epoxidation, Negishi alkyl-aryl cross-coupling, and the synthesis of dental adhesives.
What is the CAS number and formula for Diethyl 2-bromoethylphosphonate?
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The CAS number is 5324-30-1 and the linear formula is BrCH2CH2P(O)(OCH2CH3)2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Diethyl 2-bromoethylphosphonate with an assay of 97%. This is a technical grade product and is not represented as USP, BP, EP, or other pharmacopoeia grades.
What are the safety and handling considerations for Diethyl 2-bromoethylphosphonate?
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Diethyl 2-bromoethylphosphonate has a flash point of 110 °C (230 °F) and is classified under WGK 2 in Germany. Appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection, should be used. Please consult the Safety Data Sheet for detailed handling procedures.
How can I request a sample or quote for Diethyl 2-bromoethylphosphonate?
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To request a sample or quote, please contact our sales team through the website or by phone, providing the product name and CAS number (5324-30-1).
Is Diethyl 2-bromoethylphosphonate shipped internationally?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including Diethyl 2-bromoethylphosphonate, and can arrange for international shipment.
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