4-Ethoxyphenylmagnesium bromide solution
4-Ethoxyphenylmagnesium bromide solution (CAS 41842-30-2), empirical formula C8H9BrMgO, presents as a vital organometallic reagent. It is supplied as a 1 M solution in Tetrahydrofuran (THF) with a density of 1.004 g/mL at 25 °C. This Grignard reagent is instrumental in organic synthesis, facilitating carbon-carbon bond formation for constructing complex molecules.
Carbon-Carbon Bond Formation
As a Grignard reagent, 4-ethoxyphenylmagnesium bromide is extensively used in organic synthesis to create new carbon-carbon bonds. It reacts with electrophiles such as aldehydes, ketones, esters, and epoxides to form alcohols and other functionalised organic compounds.
Synthesis of Pharmaceutical Intermediates
This reagent is a key building block in the multi-step synthesis of complex organic molecules, including active pharmaceutical ingredients (APIs) and their precursors. Its aryl nature allows for the introduction of ethoxyphenyl moieties into target structures.
Organometallic Chemistry Research
Utilised in academic and industrial research laboratories for exploring novel synthetic pathways and developing new chemical entities. Its reactivity profile makes it a valuable tool for probing reaction mechanisms and designing new synthetic methodologies.
| Molecular weight | 225.37 |
|---|---|
| Empirical formula | C8H9BrMgO |
| Density | 1.004 g/mL at 25 °C |
| Concentration | 1 M in THF |
Hazard statements
- H225Highly flammable liquid and vapour
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Flash point | -17 °C / 1.4 °F |
|---|---|
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 11-14-19-34-37-40 |
| Safety statements (S) | 16-26-36/37/39-45 |
| Supplemental hazards | May form explosive peroxides., Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Ethoxyphenylmagnesium bromide solution used for?
+
4-Ethoxyphenylmagnesium bromide solution is a Grignard reagent primarily used for carbon-carbon bond formation in organic synthesis, including the preparation of pharmaceutical intermediates and in organometallic chemistry research.
What is the CAS number and formula for 4-Ethoxyphenylmagnesium bromide solution?
+
The CAS number is 41842-30-2 and the empirical formula is C8H9BrMgO.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 4-Ethoxyphenylmagnesium bromide solution at a concentration of 1 M in THF. This is a technical grade reagent suitable for general chemical synthesis and research purposes; TSS does not represent it as USP, BP, or EP grade.
How should 4-Ethoxyphenylmagnesium bromide solution be handled safely?
+
This solution is highly flammable (flash point -17 °C) and corrosive, reacting violently with water and potentially forming explosive peroxides. Handle under an inert atmosphere, away from ignition sources, in well-ventilated areas. Wear appropriate personal protective equipment (gloves, eye protection, protective clothing).
How is 4-Ethoxyphenylmagnesium bromide solution packed and shipped?
+
4-Ethoxyphenylmagnesium bromide solution is typically packed in specialised containers suitable for hazardous and flammable liquids, adhering to international shipping regulations (UN 2924 8(3) / PGII). TSS is a global supplier and exporter of fine chemicals.
How can I request a sample or quote for 4-Ethoxyphenylmagnesium bromide solution?
+
To request a sample or a formal quotation, please contact the Tech Serve Solutions sales department via our website or direct email, providing your specific requirements and shipping details.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis