4-Ethoxyphenylboronic acid
4-Ethoxyphenylboronic acid (CAS: 22237-13-4), with the molecular formula C2H5OC6H4B(OH)2 and a molecular weight of 165.98 g/mol, is a valuable aryl boronic acid derivative. It serves as a key reactant in Suzuki cross-coupling reactions. Its utility extends to the synthesis of diverse biologically active molecules, including potential therapeutic agents for conditions such as spinal muscular atrophy and various cancers.
- IUPAC
- 4-Ethoxybenzeneboronic acid
- Synonyms
- 4-Ethoxybenzeneboronic acid

Suzuki Cross-Coupling Reactions
Serves as a critical building block in palladium-catalyzed Suzuki cross-coupling reactions, facilitating the formation of carbon-carbon bonds.
Synthesis of Biologically Active Molecules
Utilised in the development of novel therapeutic agents, including modulators for spinal muscular atrophy and inhibitors for microtubule and hydroxysteroid dehydrogenase activity.
Antitumor Agent Development
Involved in the synthesis of compounds, such as amino-trimethoxyphenyl-aryl thiazoles, investigated for their potential as antitumor agents.
Immunosuppressive and Anti-inflammatory Agents
A reactant in the synthesis pathways for compounds explored for dual immunosuppressive and anti-inflammatory properties.
| Molecular weight | 165.98 |
|---|---|
| Linear formula | C2H5OC6H4B(OH)2 |
| Application | Reactant involved in Suzuki cross coupling reactions1Reactant involved in the synthesis of biologically active molecules including:• Novel modulators of survival motor neuron protein for treatment of spinal muscular atrophy2• Amino-trimethoxyphenyl-aryl thiazoles for use as microtubule inhibitors and antitumor agents3• Bicyclic hydroxyphenyl methanone derivatives for use as hydroxysteroid dehydrogenase inhibitors4• Dual immunosuppressive and anti-inflammatory agents5• Antiproliferatives via Suzuki cross-coupling / amination reactions6 |
| Melting point | 121-128 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Ethoxyphenylboronic acid used for?
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4-Ethoxyphenylboronic acid is primarily used as a reactant in Suzuki cross-coupling reactions and in the synthesis of various biologically active molecules, including potential therapeutic agents.
What is the CAS number and formula for 4-Ethoxyphenylboronic acid?
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The CAS number is 22237-13-4 and the molecular formula is C2H5OC6H4B(OH)2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Ethoxyphenylboronic acid. The exact grade and purity are detailed in the product specifications. We do not represent this product as USP, BP, or EP grade unless explicitly stated.
How should 4-Ethoxyphenylboronic acid be handled safely?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Refer to the safety data sheet for comprehensive guidance.
Is 4-Ethoxyphenylboronic acid a controlled substance?
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The provided data does not indicate that 4-Ethoxyphenylboronic acid is a controlled substance.
How is 4-Ethoxyphenylboronic acid packed, shipped, and exported?
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Tech Serve Solutions offers robust packing solutions suitable for chemical integrity during transport. We are experienced global exporters of fine chemicals and laboratory reagents.
How can I request a sample or quote for 4-Ethoxyphenylboronic acid?
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To request a sample or a quote, please contact our sales team through the website or direct contact details provided.
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