4-(Dimethylamino)pyridine, polymer-bound
Tech Serve Solutions offers 4-(Dimethylamino)pyridine, polymer-bound (CAS: 82942-26-5), a supported organic base with a molecular weight of 104.15 g/mol. This material features a DMAP loading of approximately 3.0 mmol/g on a crosslinked polystyrene matrix (2% DVB) with a particle size of 200-400 mesh. It is widely employed in chemical synthesis, particularly in acylation and esterification reactions where ease of separation is advantageous.
- Synonyms
- DMAP-polymer-bound4-DMAP resinPyridine, 4-(dimethylamino)-, polymer-bound
Catalysis in Organic Synthesis
As a polymer-supported nucleophilic catalyst, it efficiently promotes acylation, esterification, and other base-catalysed reactions. The solid support facilitates straightforward catalyst recovery and purification of reaction products.
Solid-Phase Peptide Synthesis
Its polymer-bound nature makes it suitable for solid-phase synthesis methodologies, including peptide synthesis, where it can act as a non-nucleophilic base to scavenge acids generated during coupling steps.
Chromatographic Derivatization
Used as a derivatizing reagent, particularly in HPLC applications, to improve the detection and separation of analytes by introducing a UV-absorbing tag.
Research and Development
A versatile reagent for laboratory-scale research, enabling cleaner reaction protocols and simplifying work-up procedures compared to its homogeneous counterpart.
| Molecular weight | 104.15 |
|---|---|
| Empirical formula | C8H8 |
| Particle size | 200-400 mesh |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
| Anion traces | chloride (Cl-): ≤5000 mg/kg |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Extent Of Labeling | ~3.0 mmol/g \"DMAP\" loading |
|---|---|
| Matrix | crosslinked with 2% DVB |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-(Dimethylamino)pyridine, polymer-bound used for?
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4-(Dimethylamino)pyridine, polymer-bound is primarily used as a catalyst in organic synthesis, particularly for acylation and esterification reactions, and as a derivatizing reagent in chromatography. Its solid-supported nature allows for easy separation from reaction mixtures.
What are the CAS number and formula for 4-(Dimethylamino)pyridine, polymer-bound?
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The CAS number is 82942-26-5. The empirical formula is C8H8, with a molecular weight of 104.15 g/mol.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-(Dimethylamino)pyridine, polymer-bound with an approximate DMAP loading of 3.0 mmol/g on a crosslinked polystyrene matrix (2% DVB), particle size 200-400 mesh. This product is intended for research and technical applications and is not supplied as USP, BP, or EP grade.
How should 4-(Dimethylamino)pyridine, polymer-bound be handled?
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This compound is a warning substance that causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Always wear safety eyeshields and gloves, and use a P1 (EN143) or N95 (US) respirator when handling. Ensure good ventilation.
How is 4-(Dimethylamino)pyridine, polymer-bound packed and shipped?
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Tech Serve Solutions exports fine chemicals globally, adhering to strict safety and regulatory standards for packaging and shipping, including specified anion traces such as chloride (Cl-): ≤5000 mg/kg.
How can I request a sample or quote for 4-(Dimethylamino)pyridine, polymer-bound?
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To request a sample or quote, please visit the Tech Serve Solutions website and navigate to the product page for 4-(Dimethylamino)pyridine, polymer-bound (CAS: 82942-26-5) to use our online inquiry form.
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