D-Thyroxine
D-Thyroxine (CAS: 51-49-0), with the molecular formula C15H11I4NO4 and a molecular weight of 776.87, is a synthetic iodinated derivative of the amino acid tyrosine. This compound is primarily utilised in chemical biology and synthesis, particularly within peptide chemistry and as an unnatural amino acid derivative. D-Thyroxine serves as a valuable reagent for research and development purposes, contributing to advancements in various scientific disciplines.
- IUPAC
- 3,3′,5,5′-Tetraiodo-D-thyronine,3-[4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-D-alanine
- Synonyms
- 3,3′,5,5′-Tetraiodo-D-thyronine3-[4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-D-alanine

Chemical Biology Research
D-Thyroxine is employed as a research tool in chemical biology to investigate biological pathways and molecular interactions. Its structural similarity to natural thyroid hormones makes it useful for studying receptor binding and cellular responses.
Peptide Synthesis
As an unnatural amino acid derivative, D-Thyroxine can be incorporated into peptides during synthesis. This allows for the creation of modified peptides with altered properties for research into peptide function and drug discovery.
Chemical Synthesis Reagent
The compound serves as a building block or reagent in complex organic synthesis. Its unique iodinated structure makes it suitable for specific synthetic transformations in the development of novel chemical entities.
| Molecular weight | 776.87 |
|---|---|
| Empirical formula | C15H11I4NO4 |
| Assay | 99% |
| Melting point | ~235 °C (dec.) |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is D-Thyroxine used for?
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D-Thyroxine is primarily used in chemical biology research, peptide synthesis, and as a reagent in chemical synthesis due to its nature as an unnatural amino acid derivative.
What is the CAS number and molecular formula for D-Thyroxine?
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The CAS number for D-Thyroxine is 51-49-0, and its molecular formula is C15H11I4NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies D-Thyroxine with an assay of 99%. We do not represent this product as USP, BP, or EP grade; it is intended for research and laboratory use.
How should D-Thyroxine be handled?
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Handle D-Thyroxine with appropriate personal protective equipment. Refer to the Safety Data Sheet (SDS) for detailed handling, storage, and disposal information, and follow standard laboratory safety protocols.
Is D-Thyroxine a controlled substance?
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The provided data does not indicate that D-Thyroxine is a controlled substance. However, customers should always comply with their local regulations.
How is D-Thyroxine packed and shipped?
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D-Thyroxine is carefully packed to ensure stability during transit and is exported globally by Tech Serve Solutions following all relevant shipping regulations.
How can I request a sample or quote for D-Thyroxine?
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To request a sample or a quotation for D-Thyroxine, please contact our sales team through the website or by phone, providing your specific requirements.
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