2-tert-Butyl-1,1,3,3-tetramethylguanidine

CAS 29166-72-1C9H21N3Acids & Bases

2-tert-Butyl-1,1,3,3-tetramethylguanidine (CAS: 29166-72-1, C9H21N3) is a strong, non-nucleophilic organic base with a molecular weight of 171.28 g/mol. It is frequently employed in organic synthesis as a catalyst and reagent, particularly in reactions requiring a sterically hindered base. Its unique structure allows for effective deprotonation while minimising unwanted side reactions. TSS supplies this compound for research and industrial applications.

Synonyms: 3-tetramethylguanidine29166-72-1C9H21N3

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2-tert-Butyl-1,1,3,3-tetramethylguanidine (C9H21N3) — chemical structure, CAS 29166-72-1; Chemistry, fine chemical supplied by Tech Serve Solutions

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01 /Applications

Organic Synthesis Reagent

Utilised as a strong, non-nucleophilic base in various organic transformations, such as deprotonations, eliminations, and isomerisations. Its steric bulk enhances selectivity in certain reactions.

Catalysis

Functions as an effective catalyst in polymerisation reactions and other organic processes where a sterically hindered base is beneficial. It can promote reactions that might be hindered by less bulky bases.

Building Block for Complex Molecules

Serves as a valuable building block in the synthesis of more complex organic structures and pharmaceutical intermediates. Its guanidine functionality can be incorporated into diverse molecular scaffolds.

02 /Properties

Molecular weight	171.28
Empirical formula	C9H21N3
Assay	≥97.0% (GC)
Boiling point	88-89 °C/43 mmHg(lit.)
Refractive index	n20/D 1.457

03 /Safety & handling

GHS hazard pictogram: Corrosive (GHS05) — Corrosive

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Danger

Hazard statements

H302Harmful if swallowed
H314Causes severe skin burns and eye damage

Precautionary statements

P280Wear protective gloves, clothing and eye/face protection
P305IF IN EYES
P310Immediately call a POISON CENTER or doctor

Protective equipment	Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point	65 °C / 149 °F
Transport (UN / ADR)	UN 3267 8 / PGII
Water hazard class (WGK, DE)	3
Hazard codes (EU)	C
Risk statements (R)	22-34
Safety statements (S)	26-36/37/39-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

29166-72-1

MDL number

MFCD01862972

Beilstein registry

2352408

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 2-tert-Butyl-1,1,3,3-tetramethylguanidine used for?

This compound is primarily used as a strong, non-nucleophilic organic base in organic synthesis and catalysis. It is valuable for deprotonation reactions and as a building block in the synthesis of complex molecules.

What is the CAS number and molecular formula?

The CAS number for 2-tert-Butyl-1,1,3,3-tetramethylguanidine is 29166-72-1, and its molecular formula is C9H21N3.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies 2-tert-Butyl-1,1,3,3-tetramethylguanidine with an assay of ≥97.0% (GC). TSS does not represent this product as USP, BP, or EP grade.

How should 2-tert-Butyl-1,1,3,3-tetramethylguanidine be handled?

This compound is classified as Dangerous and causes severe skin burns and eye damage (H314), and is harmful if swallowed (H302). Appropriate personal protective equipment, including gloves, goggles, and suitable respiratory protection, must be worn. Handle with extreme caution in a well-ventilated area.

How is this chemical packed and exported?

2-tert-Butyl-1,1,3,3-tetramethylguanidine is shipped as a UN 3267, Class 8, Packing Group II hazardous material, adhering to all relevant international shipping and export regulations for dangerous goods.

How can I request a sample or quote?

To request a sample or a quotation for 2-tert-Butyl-1,1,3,3-tetramethylguanidine, please contact the Tech Serve Solutions sales team via our website or direct contact details.