4-Chlorophenyl dichlorophosphate

CAS 772-79-2Cl2P(O)OC6H4ClCatalysis & Inorganic

4-Chlorophenyl dichlorophosphate (CAS 772-79-2, Cl2P(O)OC6H4Cl) is a chemical compound with a molecular weight of 245.43 g/mol. It serves as a valuable reactant in organic synthesis, primarily utilized as a phosphorylation agent. Its applications include the preparation of various biologically active compounds, such as antimicrobial, antioxidant, and antitumor agents, as well as nucleotide anti-viral prodrugs. This compound is supplied by Tech Serve Solutions for research and chemical synthesis purposes.

IUPAC: 4-Chlorophenyl dichlorophosphinate,4-Chlorophenyl phosphorodichloridate,p-Chlorophenyl dichlorophosphate
Synonyms: 4-Chlorophenyl phosphorodichloridate4-Chlorophenyl dichlorophosphinatep-Chlorophenyl dichlorophosphate

Email us

4-Chlorophenyl dichlorophosphate (Cl2P(O)OC6H4Cl) — chemical structure, CAS 772-79-2; Chemistry, fine chemical supplied by Tech Serve Solutions

Chemical SynthesisPhosphine CompoundsPhosphorus Precursors

01 /Applications

Synthesis of Antimicrobial and Antioxidant Agents

4-Chlorophenyl dichlorophosphate is a key reactant in the preparation of antimicrobial and antioxidant agents. It facilitates the introduction of the phosphoryl group, crucial for the biological activity of these compounds.

Preparation of Antitumor Compounds

This compound is employed in the synthesis of antitumor agents. Its reactivity allows for the construction of complex molecules with potential therapeutic applications in cancer treatment.

Nucleotide Anti-viral Prodrug Synthesis

4-Chlorophenyl dichlorophosphate serves as a precursor in the development of nucleotide anti-viral prodrugs. It plays a role in modifying nucleotide structures for enhanced antiviral efficacy.

Phosphorylation Agent

As a phosphorylation agent, this chemical is broadly used in organic synthesis to introduce phosphate groups onto various substrates. This is a fundamental reaction in the synthesis of numerous organophosphorus compounds.

02 /Properties

Molecular weight	245.43
Linear formula	Cl2P(O)OC6H4Cl
Assay	99%
Boiling point	142 °C/11 mmHg(lit.)
Density	1.508 g/mL at 25 °C(lit.)
Refractive index	n20/D 1.539(lit.)
Application	Reactant for preparation of:• Antimicrobial agents1• Antioxidant agents2• Antitumor agents3• Nucleotide anti-viral prodrug4 Used as:• Phosphorylation agent5

03 /Safety & handling

GHS hazard pictogram: Corrosive (GHS05) — Corrosive

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P280Wear protective gloves, clothing and eye/face protection
P305IF IN EYES
P310Immediately call a POISON CENTER or doctor

Protective equipment	Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point	106 °C / 222.8 °F
Transport (UN / ADR)	UN 3265 8 / PGII
Water hazard class (WGK, DE)	3
Hazard codes (EU)	C
Risk statements (R)	14-34
Safety statements (S)	26-36/37/39-45
Supplemental hazards	Reacts violently with water.

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

772-79-2

MDL number

MFCD00009705

PubChem substance

24854091

Beilstein registry

910754

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 4-Chlorophenyl dichlorophosphate used for?

4-Chlorophenyl dichlorophosphate is used as a reactant for the preparation of antimicrobial agents, antioxidant agents, antitumor agents, and nucleotide anti-viral prodrugs. It also functions as a general phosphorylation agent in chemical synthesis.

What is the CAS number and chemical formula for 4-Chlorophenyl dichlorophosphate?

The CAS number is 772-79-2 and the chemical formula is Cl2P(O)OC6H4Cl.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies 4-Chlorophenyl dichlorophosphate with a minimum assay of 99%. This product is intended for research and chemical synthesis and is not represented as USP, BP, EP, or any other pharmacopoeial grade.

How should 4-Chlorophenyl dichlorophosphate be handled safely?

4-Chlorophenyl dichlorophosphate is a corrosive substance that reacts violently with water. Handle with extreme care, wearing appropriate personal protective equipment including faceshields, gloves, goggles, and a suitable respirator. Ensure adequate ventilation. It is classified under GHS05 with the signal word 'Danger' and hazard statement H314 (Causes severe skin burns and eye damage).

Is 4-Chlorophenyl dichlorophosphate available for export?

Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 4-Chlorophenyl dichlorophosphate. Please contact us for export inquiries.

How can I request a quote or sample for 4-Chlorophenyl dichlorophosphate?

To request a quote or sample for 4-Chlorophenyl dichlorophosphate, please contact our sales team through the website or by phone. Provide your contact details and the quantity required.