4-(Dimethylamino)phenyldiphenylphosphine
4-(Dimethylamino)phenyldiphenylphosphine (CAS 739-58-2) is a tertiary phosphine compound with the molecular formula (CH3)2NC6H4P(C6H5)2 and a molecular weight of 305.35 g/mol. This compound serves as a valuable catalyst and reducing agent in various organic synthesis applications. Its specific phosphine structure enables its use in promoting key reactions, contributing to advancements in chemical synthesis and catalysis.
- IUPAC
- 4-(Dimethylamino)triphenylphosphine,4-(Diphenylphosphino)-N,N-dimethyl-benzenamine,4-(Diphenylphosphino)-N,N-dimethylaniline
- Synonyms
- 4-(Dimethylamino)triphenylphosphine4-(Diphenylphosphino)-N,N-dimethyl-benzenamine4-(Diphenylphosphino)-N,N-dimethylaniline
Catalysis in Organic Synthesis
This phosphine is employed as a catalyst in reactions such as the preparation of dicyano(aryl)cyclohexenecarboxylic acid esters via regioselective annulation and the diastereoselective cycloaddition of styrenyl allenoates.
Interfacial Carbonylation
It facilitates the interfacial carbonylation of methylbenzyl bromide, a crucial step in certain synthetic pathways.
Hydroformylation Reactions
4-(Dimethylamino)phenyldiphenylphosphine acts as a catalyst in the hydroformylation of octene, contributing to the synthesis of aldehydes.
Selective Peptide Cleavage
This compound functions as a reducing agent for the selective cleavage of disulfide-internally linked peptide-nucleic acids.
| Molecular weight | 305.35 |
|---|---|
| Linear formula | (CH3)2NC6H4P(C6H5)2 |
| Assay | 95% |
| Application | Catalyst for:• Preparation of dicyano(aryl)cyclohexenecarboxylic acid esters via regioselective annulation1• Diastereoselective cycloaddition of styrenyl allenoates2• Interfacial carbonylation of methylbenzyl bromide3• Hydroformylation of octene4Reducing agent for selectivity of disulfide-internally linked peptide-nucleic acid cleavage5 |
| Melting point | 151-154 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-(Dimethylamino)phenyldiphenylphosphine used for?
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4-(Dimethylamino)phenyldiphenylphosphine (CAS 739-58-2) is primarily used as a catalyst in various organic synthesis reactions, including annulation, cycloaddition, carbonylation, and hydroformylation. It also functions as a reducing agent for peptide-nucleic acid cleavage.
What are the CAS number and chemical formula for 4-(Dimethylamino)phenyldiphenylphosphine?
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The CAS number for 4-(Dimethylamino)phenyldiphenylphosphine is 739-58-2. Its linear formula is (CH3)2NC6H4P(C6H5)2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-(Dimethylamino)phenyldiphenylphosphine with an assay of 95%. This is a research-grade chemical, and TSS does not represent it as USP, BP, EP, or pharmacopoeia grade.
How should 4-(Dimethylamino)phenyldiphenylphosphine be handled safely?
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Warning: This compound causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Use a dust mask type N95, eyeshields, and gloves. Ensure adequate ventilation. Refer to the Safety Data Sheet for full handling instructions.
How is 4-(Dimethylamino)phenyldiphenylphosphine packed and exported?
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As a specialist global supplier, Tech Serve Solutions expertly packs and exports 4-(Dimethylamino)phenyldiphenylphosphine, adhering to all relevant international shipping regulations for chemical compounds.
How can I request a sample or quote for 4-(Dimethylamino)phenyldiphenylphosphine?
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To request a sample or a detailed quotation for 4-(Dimethylamino)phenyldiphenylphosphine, please contact our sales team via the website or direct email.
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