4-Carboxyphenylboronic acid
4-Carboxyphenylboronic acid (CAS: 14047-29-1), with the linear formula HO 2 CC 6 H 4 B(OH) 2 and a molecular weight of 165.94, is a key organoboronic acid derivative. It serves as a versatile reagent in organic synthesis, particularly in cross-coupling reactions and functionalisation processes. This compound is essential for researchers and manufacturers engaged in the development of novel materials and complex organic molecules.
- IUPAC
- 4-(Dihydroxyboronyl)benzoic acid,4-(Dihydroxyboryl)benzoic acid,4-Carboxybenzeneboronic acid,4-Carboxylphenylboronic acid,4-Hydroxycarbonylphenyl boronic acid,4-Boronobenzoic acid,NSC 221170,p-Carboxybenzeneboronic acid,p-Carboxyphenylboronic acid,p-Boronobenzoic acid
- Synonyms
- 4-(Dihydroxyboronyl)benzoic acid4-(Dihydroxyboryl)benzoic acid4-Carboxybenzeneboronic acid4-Carboxyphenylboronic acid4-Hydroxycarbonylphenyl boronic acid4-Boronobenzoic acidNSC 221170p-Carboxybenzeneboronic acidp-Carboxyphenylboronic acidp-Boronobenzoic acid
Suzuki Coupling Reactions
4-Carboxyphenylboronic acid is a valuable substrate in palladium-catalyzed Suzuki coupling reactions, enabling the formation of carbon-carbon bonds for the synthesis of biaryl compounds and other complex organic structures.
Esterification Processes
This boronic acid can participate in esterification reactions, allowing for its incorporation into ester-containing molecules, which are prevalent in pharmaceuticals and materials science.
Surface Functionalisation
It is employed in the functionalisation of surfaces, such as poly-silicon nanowires, for applications like the detection of specific analytes, demonstrating its utility in sensor development.
Polymer Derivatisation
4-Carboxyphenylboronic acid can be used to derivatise polymers, such as polyvinylamine, altering their properties and enabling new applications in areas like drug delivery or diagnostics.
Condensation Reactions
The compound participates in condensation reactions with stabilising chains, which have been utilised in the surface modification of polystyrene latex particles.
| Molecular weight | 165.94 |
|---|---|
| Linear formula | HO2CC6H4B(OH)2 |
| Application | Reactant involved in:• Condensation reactions with stabilizer chains at the surface of polystyrene latex1• Suzuki coupling reactions2• Esterification3• Derivatization of polyvinylamine4• Synthesis of isotopically labeled mercury5• Functionalization of poly-SiNW for detection of dopamine6 |
| Melting point | 220 °C (dec.)(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 2 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Carboxyphenylboronic acid used for?
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4-Carboxyphenylboronic acid is primarily used as a reagent in organic synthesis, including Suzuki coupling reactions, esterification, polymer derivatisation, and surface functionalisation.
What is the CAS number and formula for 4-Carboxyphenylboronic acid?
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The CAS number is 14047-29-1 and the linear formula is HO 2 CC 6 H 4 B(OH) 2 .
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Carboxyphenylboronic acid as a research or technical grade material. We do not represent it as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated.
How should 4-Carboxyphenylboronic acid be handled and stored?
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Handle 4-Carboxyphenylboronic acid with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Store in a cool, dry place away from incompatible materials. Refer to the Safety Data Sheet for detailed information.
Is 4-Carboxyphenylboronic acid a controlled substance?
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Based on the provided data, 4-Carboxyphenylboronic acid is not listed as a controlled substance.
How is 4-Carboxyphenylboronic acid packed, shipped, and exported?
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Tech Serve Solutions packs and ships 4-Carboxyphenylboronic acid in compliance with all relevant regulations for domestic and international export. Packaging is designed to ensure product integrity and safety during transit.
How can I request a sample or quote for 4-Carboxyphenylboronic acid?
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To request a sample or a quote for 4-Carboxyphenylboronic acid, please contact our sales department through the website or by phone. Please provide your contact details and the quantity required.
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