4-Chloro-(N-Boc)aniline

CAS 18437-66-6ClC6H4NHCO2C(CH3)3Chemical Synthesis

4-Chloro-N-(tert-butoxycarbonyl)aniline (CAS 18437-66-6) is a crucial organic building block. With a molecular weight of 227.69 g/mol, this protected amine serves as a versatile intermediate in complex chemical synthesis. Its structure, featuring a Boc-protected aniline moiety, allows for selective reactions, making it valuable in the development of pharmaceuticals and other fine chemicals. Tech Serve Solutions offers this compound for research and development purposes.

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4-Chloro-(N-Boc)aniline (ClC6H4NHCO2C(CH3)3) — chemical structure, CAS 18437-66-6; Chemistry, fine chemical supplied by Tech Serve Solutions

Building BlocksChemical SynthesisNitrogen CompoundsOrganic Building BlocksProtected Amines

01 /Applications

Pharmaceutical Intermediate

Utilised in the multi-step synthesis of active pharmaceutical ingredients (APIs). Its protected amine functionality allows for regioselective modifications critical in drug discovery pathways.

Organic Synthesis Reagent

Serves as a key building block in constructing complex organic molecules. The Boc group can be selectively removed under specific conditions, enabling further functionalization.

Materials Science Research

Employed in the development of novel organic materials where specific electronic or structural properties are desired. Its incorporation can influence the characteristics of polymers or functional dyes.

02 /Properties

Molecular weight	227.69
Linear formula	ClC6H4NHCO2C(CH3)3
Assay	97%
Melting point	102-106 °C(lit.)

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

18437-66-6

MDL number

MFCD00816772

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 4-Chloro-N-(tert-butoxycarbonyl)aniline used for?

4-Chloro-N-(tert-butoxycarbonyl)aniline is primarily used as a versatile building block and intermediate in organic synthesis, particularly in the development of pharmaceuticals and fine chemicals.

What is the CAS number and formula for 4-Chloro-N-(tert-butoxycarbonyl)aniline?

The CAS number is 18437-66-6 and the linear formula is ClC6H4NHCO2C(CH3)3.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies 4-Chloro-N-(tert-butoxycarbonyl)aniline with an assay of 97%. This product is intended for research and development use and is not supplied as USP, BP, EP, or pharmacopoeia grade.

What are the safety and handling recommendations for this compound?

Appropriate personal protective equipment, including eyeshields and gloves, should be worn. A type N95 (US) or type P1 (EN143) respirator filter is recommended. It has a WGK Germany rating of 3, indicating a higher level of hazard.

How is this chemical shipped and exported?

Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, packaging and shipping products in compliance with international regulations.

How can I request a sample or quote?

Please contact our sales department via the website or by phone to request a sample or a formal quotation for 4-Chloro-N-(tert-butoxycarbonyl)aniline.