4-Carboxybenzenesulfonazide
4-Carboxybenzenesulfonazide (CAS: 17202-49-2), with the molecular formula HO2CC6H4SO2N3 and a molecular weight of 227.20 g/mol, is a specialised organic azide. It serves as a valuable building block in chemical synthesis, particularly for azidation and C-X bond formation. This compound is also employed as a hydroazidation catalyst for the preparation of organoazides, finding applications in chemical biology and conjugation chemistry.
- IUPAC
- 4-(Azidosulfonyl)benzoic acid

Hydroazidation Catalyst
4-Carboxybenzenesulfonazide acts as an effective catalyst for the hydroazidation reaction, facilitating the facile preparation of organoazides. This process is crucial for introducing azide functionalities into organic molecules.
Azidation Reagent
As an organic azide, it is employed in various azidation reactions. This includes its use as a reagent for introducing the azide group (N3) in the synthesis of complex organic structures and intermediates.
Building Block in Organic Synthesis
Its unique structure makes it a versatile building block for constructing more complex molecules. It is particularly useful in C-X bond formation reactions, excluding halogenation.
Chemical Biology and Conjugation Chemistry
The compound finds utility in areas such as chemical biology and conjugation chemistry, where the azide functionality is essential for bioconjugation strategies, such as click chemistry.
| Molecular weight | 227.20 |
|---|---|
| Linear formula | HO2CC6H4SO2N3 |
| Assay | 97% |
| Storage temperature | 2-8°C |
| Application | Hydroazidation Catalyst for Facile Preparation of Organoazides |
| Melting point | 180 °C (dec.)(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Carboxybenzenesulfonazide used for?
+
4-Carboxybenzenesulfonazide is used as a hydroazidation catalyst for preparing organoazides, as an azidation reagent, and as a building block in organic synthesis, including applications in chemical biology and conjugation chemistry.
What are the CAS number and formula for 4-Carboxybenzenesulfonazide?
+
The CAS number is 17202-49-2 and the linear formula is HO2CC6H4SO2N3.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 4-Carboxybenzenesulfonazide with an assay of 97%. TSS does not represent this product as USP, BP, or EP grade.
How should 4-Carboxybenzenesulfonazide be handled safely?
+
Handle with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves. Avoid breathing dust. Ensure adequate ventilation. Store at 2-8°C.
Is 4-Carboxybenzenesulfonazide shipped internationally by TSS?
+
Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 4-Carboxybenzenesulfonazide, and can accommodate export orders.
How can I request a quote or sample for 4-Carboxybenzenesulfonazide?
+
Please contact our sales team through the website or by phone to request a quotation or to arrange for a sample of 4-Carboxybenzenesulfonazide.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis