4-Butylphenylboronic acid
4-Butylphenylboronic acid (CAS: 145240-28-4; Formula: C10H15BO2; Molar Mass: 178.04 g/mol) is a monosubstituted aryl boronic acid utilised in organic synthesis. It serves as a key reactant in various palladium-catalysed cross-coupling reactions, including the Suzuki-Miyaura coupling. This compound is also employed in specific catalytic systems for esterification and Heck-type reactions, making it a versatile building block for complex molecule construction.
Suzuki-Miyaura Cross-Couplings
4-Butylphenylboronic acid is a valuable substrate for Suzuki-Miyaura cross-coupling reactions. These palladium-catalysed reactions are fundamental in forming carbon-carbon bonds, essential for synthesising biaryl compounds and complex organic molecules.
NHC-Iron Catalysed Esterification
This boronic acid acts as a reactant in NHC-Iron-catalyzed aerobic oxidative aromatic esterification of aldehydes. This application demonstrates its utility in greener synthetic methodologies for functional group transformations.
Palladium-Catalyzed Oxidative Heck-Type Reactions
It functions as a reactant in palladium-catalysed oxidative Heck-type reactions. This enables the synthesis of substituted alkenes and other unsaturated compounds through efficient C-C bond formation.
| Molecular weight | 178.04 |
|---|---|
| Linear formula | CH3(CH2)3C6H4B(OH)2 |
| Application | Reactant for:Suzuki-Miyaura cross-couplings1,2NHC-Iron-catalyzed aerobic oxidative aromatic esterification of aldehydes3Palladium-catalyzed oxidative Heck-type reactions4 |
| Melting point | 91-97 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Butylphenylboronic acid used for?
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4-Butylphenylboronic acid is primarily used as a reactant in Suzuki-Miyaura cross-couplings and other palladium-catalysed reactions, including NHC-iron-catalyzed esterification and Heck-type reactions for organic synthesis.
What are the CAS number and chemical formula for 4-Butylphenylboronic acid?
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The CAS number for 4-Butylphenylboronic acid is 145240-28-4, and its chemical formula is C10H15BO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Butylphenylboronic acid typically as a research or technical grade material. We do not represent this product as meeting USP, BP, or EP pharmacopoeia standards unless explicitly stated in the product specifications.
What are the safety considerations when handling 4-Butylphenylboronic acid?
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When handling 4-Butylphenylboronic acid, it is essential to use appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Consult the Safety Data Sheet (SDS) for comprehensive hazard information.
Is 4-Butylphenylboronic acid a controlled substance?
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Based on the provided data, there is no indication that 4-Butylphenylboronic acid is a controlled substance.
How is 4-Butylphenylboronic acid packed and exported?
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Tech Serve Solutions packs and exports 4-Butylphenylboronic acid in compliance with international shipping regulations for chemical compounds. Specific packaging details are available upon request.
How can I request a sample or quote for 4-Butylphenylboronic acid?
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To request a sample or a quotation for 4-Butylphenylboronic acid, please contact our sales department via the website or by phone, providing your specific requirements.
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