4-Carboxy-TEMPO, free radical
4-Carboxy-TEMPO, free radical (CAS 37149-18-1) is a stable nitroxide radical with the molecular formula C10H18NO3 and a molecular weight of 200.25 g/mol. This compound is recognised for its utility as a radical scavenger and a spin label. It finds significant application in analytical chemistry, particularly in ESR/EPR spectroscopy, and serves as a valuable reagent in organic synthesis and radical chemistry research.
- IUPAC
- 4-Carboxy-2,2,6,6-tetramethylpiperidine 1-oxyl,4-Carboxy-2,2,6,6-tetramethylpiperidinyloxy, free radical,4-Carboxy-TEMPO
- Synonyms
- 4-Carboxy-2,2,6,6-tetramethylpiperidine 1-oxyl4-Carboxy-2,2,6,6-tetramethylpiperidinyloxy, free radical4-Carboxy-TEMPO

ESR/EPR Spectroscopy
As a stable free radical, 4-Carboxy-TEMPO is frequently employed as a spin label in Electron Spin Resonance (ESR) and Electron Paramagnetic Resonance (EPR) spectroscopy to study molecular dynamics and environments.
Organic Synthesis
This compound acts as a catalyst or co-catalyst in various oxidation reactions. Its radical nature allows it to participate in controlled radical processes and mediate specific chemical transformations.
Analytical Reagent
4-Carboxy-TEMPO serves as a valuable analytical reagent due to its paramagnetic properties, enabling its use in specific analytical methods and as a reference standard.
Radical Chemistry Research
It is extensively used in academic and industrial research settings to investigate mechanisms involving free radicals, including their generation, propagation, and termination steps.
| Molecular weight | 200.25 |
|---|---|
| Empirical formula | C10H18NO3 |
| Assay | 97% |
| Storage temperature | 2-8°C |
| Melting point | 185-189 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Carboxy-TEMPO, free radical used for?
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4-Carboxy-TEMPO, free radical is primarily used in ESR/EPR spectroscopy as a spin label, in organic synthesis as a reagent or catalyst, as an analytical reagent, and in general radical chemistry research.
What are the CAS number and formula for 4-Carboxy-TEMPO, free radical?
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The CAS number for 4-Carboxy-TEMPO, free radical is 37149-18-1, and its empirical formula is C10H18NO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Carboxy-TEMPO, free radical with an assay of 97%. This product is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should 4-Carboxy-TEMPO, free radical be handled safely?
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According to GHS, 4-Carboxy-TEMPO, free radical is a Warning substance with hazards H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Handling requires a dust mask type N95, eyeshields, and gloves. Ensure good ventilation and avoid breathing dust. In case of contact, rinse thoroughly with water. Store at 2-8°C.
How is 4-Carboxy-TEMPO, free radical packed and exported?
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Tech Serve Solutions expertly packs and exports chemicals globally, ensuring compliance with all relevant shipping regulations for safe transport.
How can I request a quote or sample for 4-Carboxy-TEMPO, free radical?
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Please contact our sales team directly via phone or email to request a quote or a sample of 4-Carboxy-TEMPO, free radical.
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