4-Chloro-1,2-difluorobenzene
4-Chloro-1,2-difluorobenzene (CAS 696-02-6), with the linear formula ClC₆H₃F₂, is a fluorinated aromatic compound. It serves as a valuable building block in organic synthesis, particularly for the introduction of the 4-chloro-1,2-difluorophenyl moiety into more complex molecules. Its defined structure and reactivity make it a key intermediate in the development of speciality chemicals and advanced materials. Tech Serve Solutions supplies this compound for research and development purposes.
- Synonyms
- ClC6H3F21-Chloro-3,4-difluorobenzene4-Chloro-1,2-difluorobenzene

Organic Synthesis Intermediate
Utilised as a building block in the synthesis of various organic compounds. Its specific substitution pattern makes it useful for introducing the 4-chloro-1,2-difluorophenyl group into target molecules.
Pharmaceutical Research
Serves as a precursor or intermediate in the multi-step synthesis pathways for novel pharmaceutical candidates. The presence of fluorine atoms can influence the pharmacokinetic properties of drug molecules.
Agrochemical Development
Can be employed in the design and synthesis of new agrochemical agents. The fluorinated aromatic structure may contribute to enhanced efficacy or specific biological activity.
Materials Science
Potentially used in the creation of speciality polymers or advanced materials where its unique chemical structure can impart desired physical or chemical properties.
| Molecular weight | 148.54 |
|---|---|
| Linear formula | ClC6H3F2 |
| Assay | 98% |
| Boiling point | 126 °C(lit.) |
| Density | 1.33 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.475(lit.) |


Hazard statements
- H226Flammable liquid and vapour
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 35 °C / 95 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 10-22-36/37/38 |
| Safety statements (S) | 16-26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Chloro-1,2-difluorobenzene primarily used for?
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4-Chloro-1,2-difluorobenzene is primarily used as a building block and intermediate in organic synthesis for the development of speciality chemicals, pharmaceuticals, and agrochemicals.
What is the CAS number and formula for 4-Chloro-1,2-difluorobenzene?
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The CAS number is 696-02-6, and its linear formula is ClC₆H₃F₂.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Chloro-1,2-difluorobenzene with a minimum assay of 98%. This product is supplied for research and laboratory use and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should 4-Chloro-1,2-difluorobenzene be handled safely?
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Handle 4-Chloro-1,2-difluorobenzene with appropriate personal protective equipment, including safety glasses, gloves, and respiratory protection suitable for organic vapours (e.g., ABEK filter). Ensure adequate ventilation, as it is flammable (Flash Point 35 °C) and can cause skin, eye, and respiratory irritation. Avoid ignition sources.
Is 4-Chloro-1,2-difluorobenzene flammable?
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Yes, 4-Chloro-1,2-difluorobenzene is flammable, with a flash point of 35 °C (95 °F).
How is 4-Chloro-1,2-difluorobenzene shipped?
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4-Chloro-1,2-difluorobenzene is shipped as a hazardous material under UN 1993, Class 3, Packing Group III.
How can I request a quote or sample?
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To request a quote or sample of 4-Chloro-1,2-difluorobenzene, please contact our sales team via the website or listed phone number, providing your specific requirements and shipping details.
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