4-(Bromomethyl)phenylboronic acid
4-(Bromomethyl)phenylboronic acid (CAS 68162-47-0) is an organoboron compound with the linear formula BrCH₂C₆H₄B(OH)₂ and a molecular weight of 214.85 g/mol. This aryl boronic acid serves as a versatile reactant in organic synthesis. It is involved in the design of autotaxin inhibitors, the synthesis of boronated phosphonium salts, and studies aimed at enhancing gene transfection capabilities and developing optical glucose sensors.
- IUPAC
- α-Bromo-p-tolueneboronic acid,p-Boronobenzyl bromide
- Synonyms
- α-Bromo-p-tolueneboronic acidp-Boronobenzyl bromide
Autotaxin Inhibitor Design
4-(Bromomethyl)phenylboronic acid is a key reactant in the design and synthesis of novel autotaxin inhibitors, potentially contributing to therapeutic research.
Boronated Phosphonium Salt Synthesis
This compound is utilised in the synthesis of boronated phosphonium salts, expanding the scope of organophosphorus chemistry.
Gene Transfection Enhancement
Research has investigated the incorporation of boronic acid groups, using compounds like 4-(Bromomethyl)phenylboronic acid, to improve the efficiency of gene transfection.
Optical Glucose Sensing
The positioning of boronic acid groups, facilitated by reactants such as this, is studied to optimise performance in optical glucose-sensing ensembles.
| Molecular weight | 214.85 |
|---|---|
| Linear formula | BrCH2(C6H4)B(OH)2 |
| Storage temperature | 2-8°C |
| Application | Reactant involved in:• Design of boronic acid-based autotaxin inhibitors1• Synthesis of boronated phosphonium salts2• Studies of incorporation of boronic acid groups to enhance gene transfection capability2• Investigations of the effect of boronic acid-positioning in optical glucose-sensing ensemble3 |
| Melting point | 173-177 °C |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-(Bromomethyl)phenylboronic acid used for?
+
4-(Bromomethyl)phenylboronic acid is used as a reactant in organic synthesis, including the design of autotaxin inhibitors, synthesis of boronated phosphonium salts, and studies on gene transfection and optical glucose sensing.
What is the CAS number and formula for 4-(Bromomethyl)phenylboronic acid?
+
The CAS number is 68162-47-0, and the linear formula is BrCH₂C₆H₄B(OH)₂.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies this chemical as a research or technical grade material. We do not represent it as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated in the product specifications.
How should 4-(Bromomethyl)phenylboronic acid be handled safely?
+
This compound is classified as harmful if swallowed, causes skin irritation, causes serious eye irritation, and may cause respiratory irritation (H302-H315-H319-H335). Wear appropriate personal protective equipment, including a dust mask (type N95), eyeshields, and gloves. Ensure adequate ventilation.
How is 4-(Bromomethyl)phenylboronic acid packed and shipped?
+
This product is typically packed for storage at 2-8°C. TSS exports chemicals globally; please contact us for specific shipping and export details.
How can I request a sample or quote?
+
Please contact our sales team via the website or directly to request a sample or obtain a quotation for 4-(Bromomethyl)phenylboronic acid.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis