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4-(Bromomethyl)phenyl isothiocyanate

CAS 155863-32-4C8H6BrNSChemical Synthesis

4-(Bromomethyl)phenyl isothiocyanate (CAS: 155863-32-4) is an organic compound with a molecular weight of 228.11 g/mol. This versatile hetero-bifunctional linker is primarily used as a synthetic building block. It plays a key role in chemical biology and synthesis, particularly for introducing amine or thiol reactive groups through pyridyl-nitrogen quaternisation, and in the preparation of fluorescent labels.

IUPAC
4-Isothiocyanatobenzyl bromide
Synonyms
4-Isothiocyanatobenzyl bromide
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4-(Bromomethyl)phenyl isothiocyanate (C8H6BrNS) — chemical structure, CAS 155863-32-4; Chemistry, fine chemical supplied by Tech Serve Solutions
Bifunctional LinkersBuilding BlocksChemical BiologyChemical SynthesisLinkers and CrosslinkersOrganic Building BlocksSulfur Compounds
01 /Applications

Hetero-bifunctional Linker

Utilised for the quaternisation of pyridyl-nitrogen atoms, effectively introducing reactive amine or thiol functionalities into molecules. This is crucial for conjugation and modification in various chemical and biological applications.

Fluorescent Label Synthesis

Serves as a synthetic building block in the preparation of fluorescent labels. Its structure allows for the development of novel probes for biological imaging and detection.

Organic Synthesis Building Block

A valuable intermediate in organic synthesis for creating complex molecules. Its distinct functional groups enable diverse reaction pathways.

02 /Properties
Molecular weight228.11
Empirical formulaC8H6BrNS
Assay≥98.0%
ApplicationHetero-bifunctional linker specially for the quaternisation of pyridyl-nitrogen in order to introduce an amine or thiol reactive group. Synthetic building block for the preparation of fluorescent labels1
03 /Safety & handling
GHS hazard pictogram: Toxic (GHS06)
Toxic
GHS hazard pictogram: Health hazard (GHS08)
Health hazard
Danger

Hazard statements

  • H301Toxic if swallowed
  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H334May cause allergy or asthma symptoms if inhaled
  • H335May cause respiratory irritation

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P301IF SWALLOWED
  • P305IF IN EYES
  • P342
Protective equipmentEyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Transport (UN / ADR)UN 2811 6.1 / PGIII
Water hazard class (WGK, DE)3
Hazard codes (EU)T
Risk statements (R)25-36/37/38-42
Safety statements (S)22-26-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
155863-32-4
MDL number
MFCD08702661
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 4-(Bromomethyl)phenyl isothiocyanate used for?

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4-(Bromomethyl)phenyl isothiocyanate is primarily used as a hetero-bifunctional linker for quaternising pyridyl-nitrogen to introduce amine or thiol reactive groups, and as a synthetic building block for preparing fluorescent labels.

What is the CAS number and formula for 4-(Bromomethyl)phenyl isothiocyanate?

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The CAS number is 155863-32-4 and the empirical formula (Hill notation) is C8H6BrNS.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies 4-(Bromomethyl)phenyl isothiocyanate with an assay of 098.0%. We do not represent this product as USP/BP/EP or any pharmacopoeia grade.

What are the safety considerations when handling 4-(Bromomethyl)phenyl isothiocyanate?

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This compound is classified as toxic and is an irritant. It carries significant hazards including H301 (Toxic if swallowed), H315 (Causes skin irritation), H319 (Causes serious eye irritation), H334 (May cause allergy or asthma symptoms or breathing difficulties if inhaled), and H335 (May cause respiratory irritation). Appropriate personal protective equipment including eyeshields, faceshields, gloves, and P2 respirator cartridges is essential. Ensure handling in a well-ventilated area and follow all recommended safety precautions.

How is 4-(Bromomethyl)phenyl isothiocyanate packed, shipped, and exported?

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4-(Bromomethyl)phenyl isothiocyanate is packed in compliance with international shipping regulations for hazardous materials. TSS is experienced in exporting fine chemicals globally.

How can I request a sample or quote for 4-(Bromomethyl)phenyl isothiocyanate?

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To request a sample or a quotation, please contact our sales team through the website or by calling our main office. Please specify the quantity required.

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