7-Hydroxy-3,4,8-trimethylcoumarin

CAS 91963-11-0C12H12O3Chemical Synthesis

7-Hydroxy-3,4,8-trimethylcoumarin (CAS: 91963-11-0) is a heterocyclic organic compound with the molecular formula C12H12O3 and a molecular weight of 204.22 g/mol. This coumarin derivative serves as a valuable building block in chemical synthesis. Its applications include research into melanin inhibition and as an intermediate in the preparation of other coumarin derivatives. Available from Tech Serve Solutions at 97% purity.

Synonyms: 91963-11-0

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7-Hydroxy-3,4,8-trimethylcoumarin (C12H12O3) — chemical structure, CAS 91963-11-0; Chemistry, fine chemical supplied by Tech Serve Solutions

Building BlocksChemical SynthesisCoumarinsHeterocyclic Building Blocks

01 /Applications

Melanin Inhibition Studies

7-Hydroxy-3,4,8-trimethylcoumarin has been utilised in research to investigate the impact of melanin inhibiting compounds on the pigmentation of fungal mycelia, specifically *Aspergillus bridgeri*.

Synthesis of Coumarin Derivatives

This compound functions as a precursor in the preparation of other specialized coumarin structures, such as 7-ethynyl-3,4,8-trimethylcoumarin.

Chemical Synthesis Building Block

As a heterocyclic building block, it is employed in various organic synthesis pathways for the creation of complex molecules.

02 /Properties

Molecular weight	204.22
Empirical formula	C12H12O3
Assay	97%
Application	7-Hydroxy-3,4,8-trimethylcoumarin has been used:• to investigate the effect of melanin inhibiting compounds on mycelial pigmentation of Aspergillus bridgeri grown on potato dextrose agar1• in the preparation of 7-ethynyl-3,4,8-trimethylcoumarin2
Melting point	278-280 °C(lit.)

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust, fume, gas or vapours
P305IF IN EYES

Protective equipment	dust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xi
Risk statements (R)	36/37/38
Safety statements (S)	26-37/39

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

91963-11-0

MDL number

MFCD00011569

PubChem substance

24857662

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 7-Hydroxy-3,4,8-trimethylcoumarin used for?

7-Hydroxy-3,4,8-trimethylcoumarin is used in chemical synthesis as a building block, for example, in studies on melanin inhibition and in the preparation of other coumarin derivatives.

What is the CAS number and molecular formula for 7-Hydroxy-3,4,8-trimethylcoumarin?

The CAS number is 91963-11-0 and the molecular formula is C12H12O3.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies 7-Hydroxy-3,4,8-trimethylcoumarin with an assay of 97%. We do not represent this product as USP, BP, EP or for any pharmaceutical, nutraceutical, or food use.

What are the primary hazards associated with 7-Hydroxy-3,4,8-trimethylcoumarin?

This compound is a Warning (GHS07) with hazards including skin irritation (H315), serious eye irritation (H319), and respiratory tract irritation (H335). Appropriate personal protective equipment includes a dust mask (N95), eyeshields, and gloves.