4-(Bromomethyl)phenylacetic acid
4-(Bromomethyl)phenylacetic acid (CAS: 13737-36-5) is a valuable organic building block with the linear formula BrCH₂C₆H₄CH₂CO₂H and a molecular weight of 229.07 g/mol. This carboxylic acid derivative is primarily utilised as a precursor in organic synthesis, notably in the development of pharmaceutical intermediates and specialised chemical compounds. Its reactive bromomethyl group and carboxylic acid functionality make it a versatile reagent for constructing complex molecular architectures in research and development settings.
Serine Protease Inhibitor Precursor
4-(Bromomethyl)phenylacetic acid serves as a key intermediate in the synthesis of serine protease inhibitors. This application leverages its structure to build molecules designed to modulate the activity of these important enzymes.
Crown Ether Receptor Synthesis
The compound is employed in the creation of novel crown ether receptors. Its incorporation into these structures allows for the development of specialised molecules capable of binding and transporting specific ions or molecules.
Organic Synthesis Building Block
As a versatile building block, 4-(Bromomethyl)phenylacetic acid is used in a wide range of organic synthesis pathways. It is suitable for introducing specific functional groups and structural motifs into target molecules for research purposes.
| Molecular weight | 229.07 |
|---|---|
| Linear formula | BrCH2C6H4CH2CO2H |
| Assay | 95% |
| Application | Precursor for serine protease inhibitor.1 Used in the synthesis of a novel crown ether receptor.2 |
| Melting point | 179-183 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H334May cause allergy or asthma symptoms if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
- P342
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38-42 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-(Bromomethyl)phenylacetic acid used for?
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4-(Bromomethyl)phenylacetic acid is used as a precursor for serine protease inhibitors and in the synthesis of novel crown ether receptors. It also serves as a general building block in organic synthesis.
What are the CAS number and formula for 4-(Bromomethyl)phenylacetic acid?
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The CAS number for 4-(Bromomethyl)phenylacetic acid is 13737-36-5, and its linear formula is BrCH₂C₆H₄CH₂CO₂H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-(Bromomethyl)phenylacetic acid with an assay of 95%. This is a technical/research grade material, and TSS does not represent it as USP, BP, or EP grade.
What are the safety and handling considerations for 4-(Bromomethyl)phenylacetic acid?
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4-(Bromomethyl)phenylacetic acid is labelled with GHS07 and GHS08 symbols and carries a Danger signal word. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335) and allergy or asthma symptoms or breathing difficulties if inhaled (H334). Appropriate personal protective equipment, including a dust mask type N95, eyeshields, face shields, and gloves, must be used. Handle in a well-ventilated area, avoid breathing dust, and ensure proper procedures are followed.
How is 4-(Bromomethyl)phenylacetic acid packed, shipped, and exported?
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Tech Serve Solutions packs, ships, and exports chemicals according to international regulations and best practices to ensure safe transit and product integrity.
How can I request a sample or quote for 4-(Bromomethyl)phenylacetic acid?
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To request a sample or a quote for 4-(Bromomethyl)phenylacetic acid, please contact the Tech Serve Solutions sales team through our website or by phone.
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