4-(Bromomethyl)benzenesulfonyl chloride
4-(Bromomethyl)benzenesulfonyl chloride (CAS 66176-39-4) is a key organic building block with the linear formula BrCH<sub>2</sub>C<sub>6</sub>H<sub>4</sub>SO<sub>2</sub>Cl and a molecular weight of 269.54 g/mol. This sulfonyl halide serves as a versatile intermediate in organic synthesis, particularly for introducing the 4-(bromomethyl)benzenesulfonyl moiety into target molecules. It is primarily utilised in research and development settings for the creation of novel chemical entities.
- IUPAC
- α-Bromo-p-toluenesulfonyl chloride
- Synonyms
- α-Bromo-p-toluenesulfonyl chloride
Organic Synthesis Intermediate
Serves as a crucial intermediate for the synthesis of complex organic molecules. Its reactive bromomethyl and sulfonyl chloride groups allow for diverse derivatisation pathways in multi-step chemical processes.
Reagent for Functionalisation
Used to introduce the 4-(bromomethyl)benzenesulfonyl group onto various substrates. This functionalisation is valuable in creating specialised chemical structures for research purposes.
Pharmaceutical Intermediate Research
Applicable in exploratory synthesis for potential pharmaceutical leads. Its structure can be incorporated into molecules designed for biological activity screening.
| Molecular weight | 269.54 |
|---|---|
| Linear formula | BrCH2C6H4SO2Cl |
| Assay | 95% |
| Melting point | 71-75 °C(lit.) |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-(Bromomethyl)benzenesulfonyl chloride primarily used for?
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4-(Bromomethyl)benzenesulfonyl chloride is primarily used as a versatile intermediate in organic synthesis and for the functionalisation of molecules in research and development.
What is the CAS number and formula for 4-(Bromomethyl)benzenesulfonyl chloride?
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The CAS number is 66176-39-4 and the linear formula is BrCH2C6H4SO2Cl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-(Bromomethyl)benzenesulfonyl chloride with an assay of 95%. This product is suitable for research and chemical synthesis; TSS does not represent it as USP, BP, or EP grade.
How should 4-(Bromomethyl)benzenesulfonyl chloride be handled?
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This compound is classified as corrosive (H314) and causes severe skin burns and eye damage. Handle with appropriate personal protective equipment, including eyeshields, face shields, chemical-resistant gloves, and respiratory protection, in a well-ventilated area or fume hood. Refer to the Safety Data Sheet for full handling instructions.
How is 4-(Bromomethyl)benzenesulfonyl chloride packed and shipped?
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4-(Bromomethyl)benzenesulfonyl chloride is packed in compliance with transport regulations for hazardous materials, including UN 3261, Class 8, Packing Group II. It is available for export worldwide by TSS.
How can I request a sample or quote for 4-(Bromomethyl)benzenesulfonyl chloride?
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To request a sample or a quotation, please use the contact form on the Tech Serve Solutions website or email our sales department directly, referencing the product name and CAS number.
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