4-(Boc-aminomethyl)benzoic acid
4-(Boc-aminomethyl)benzoic acid (CAS: 33233-67-9) is a protected amino acid derivative with a molecular weight of 251.28 g/mol. This compound features a benzoic acid moiety with a tert-butoxycarbonyl (Boc)-protected aminomethyl group. It serves as a valuable building block in organic synthesis, particularly in peptide chemistry and the development of unnatural amino acid derivatives for applications in chemical biology and medicinal chemistry research.

Peptide Synthesis
Utilised as a protected amino acid building block for the incorporation of modified residues into peptide chains, enabling the synthesis of novel peptides with tailored properties.
Medicinal Chemistry
Serves as an intermediate in the synthesis of potential drug candidates and biologically active molecules where a functionalised benzoic acid scaffold is required.
Chemical Biology Research
Employed in the creation of probes and labelled molecules for investigating biological pathways and protein interactions.
Organic Synthesis Intermediate
A versatile reagent for constructing complex organic molecules, leveraging the reactivity of both the carboxylic acid and the protected amine functionalities.
| Molecular weight | 251.28 |
|---|---|
| Linear formula | (CH3)3CO2CNHCH2C6H4CO2H |
| Assay | ≥98.0% (T) |
| Melting point | 164-168 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-(Boc-aminomethyl)benzoic acid used for?
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4-(Boc-aminomethyl)benzoic acid is used as a protected amino acid building block in peptide synthesis, as an intermediate in medicinal chemistry for drug discovery, and in chemical biology research for creating probes and labelled molecules. It is also a versatile intermediate in general organic synthesis.
What is the CAS number and formula for 4-(Boc-aminomethyl)benzoic acid?
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The CAS number is 33233-67-9. The linear formula is (CH3)3CO2CNHCH2C6H4CO2H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-(Boc-aminomethyl)benzoic acid with an assay of ≥98.0% (T). This is a technical grade product and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety and handling recommendations for this product?
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Handling requires appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. The compound is classified under WGK 2 (Germany). Please consult the Safety Data Sheet (SDS) for comprehensive handling and safety information.
How is 4-(Boc-aminomethyl)benzoic acid packed and shipped?
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Tech Serve Solutions packs and exports fine chemicals, pharmaceutical intermediates, and laboratory reagents globally. Specific packing details are available upon request.
How can I request a sample or quote for 4-(Boc-aminomethyl)benzoic acid?
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To request a sample or a quote for 4-(Boc-aminomethyl)benzoic acid, please contact the TSS sales department through the website or by phone.
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