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4-(Boc-amino)benzylamine

CAS 220298-96-4C12H18N2O2Chemical Synthesis

4-(Boc-amino)benzylamine (CAS: 220298-96-4) is an organic compound with the molecular formula C12H18N2O2 and a molecular weight of 222.28 g/mol. This molecule features a tert-butyl carbamate protecting group on the amine functionality, making it a valuable intermediate in organic synthesis. It is commonly employed as a building block in the preparation of more complex molecules, particularly within the pharmaceutical and fine chemical sectors.

IUPAC
(4-Aminomethyl-phenyl)-carbamic acid tert-butyl ester,4-(Aminomethyl)-N-Boc-aniline,tert-Butyl N-[4-(aminomethyl)phenyl]carbamate
Synonyms
tert-Butyl N-[4-(aminomethyl)phenyl]carbamate(4-Aminomethyl-phenyl)-carbamic acid tert-butyl ester4-(Aminomethyl)-N-Boc-aniline
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4-(Boc-amino)benzylamine (C12H18N2O2) — chemical structure, CAS 220298-96-4; Chemistry, fine chemical supplied by Tech Serve Solutions
AminesBuilding BlocksC12C12 to C63Carbonyl CompoundsChemical SynthesisEstersNitrogen Compounds
01 /Applications

Pharmaceutical Intermediate

Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs). Its protected amine and reactive benzylamine functionalities allow for selective derivatization in multi-step synthetic routes.

Organic Synthesis Reagent

Utilised in academic and industrial research laboratories for the construction of novel organic compounds. It is particularly useful for introducing protected aminobenzyl moieties into target molecules.

Peptide Synthesis

Can be incorporated into peptide chains or used in the synthesis of peptide mimetics, leveraging its amine and benzyl functionalities for linkage and modification.

Material Science

Potential applications in the development of novel polymers or functional materials where the aminobenzyl structure can impart specific properties.

02 /Properties
Molecular weight222.28
Empirical formulaC12H18N2O2
Assay95%
Melting point107-113 °C
03 /Safety & handling
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Warning

Hazard statements

  • H302Harmful if swallowed
  • H317May cause an allergic skin reaction

Precautionary statements

  • P280Wear protective gloves, clothing and eye/face protection
Water hazard class (WGK, DE)3
Hazard codes (EU)Xn
Risk statements (R)22-43
Safety statements (S)36/37

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
220298-96-4
MDL number
MFCD02183573
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 4-(Boc-amino)benzylamine used for?

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4-(Boc-amino)benzylamine is primarily used as a building block in organic synthesis, particularly in the preparation of pharmaceutical intermediates and other complex organic molecules. Its protected amine and reactive benzylamine groups offer versatility in synthetic strategies.

What is the CAS number and molecular formula for 4-(Boc-amino)benzylamine?

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The CAS number for 4-(Boc-amino)benzylamine is 220298-96-4, and its molecular formula is C12H18N2O2.

What grade and purity does Tech Serve Solutions supply for 4-(Boc-amino)benzylamine?

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Tech Serve Solutions supplies 4-(Boc-amino)benzylamine with an assay of 95%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.

How should 4-(Boc-amino)benzylamine be handled safely?

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4-(Boc-amino)benzylamine is classified with a GHS07 symbol and a 'Warning' signal word. It carries hazard statements H302 (Harmful if swallowed) and H317 (May cause an allergic skin reaction). Handle with appropriate personal protective equipment, including gloves and protective clothing, and avoid ingestion and skin contact. Please refer to the Safety Data Sheet (SDS) for comprehensive handling information.

How is 4-(Boc-amino)benzylamine packed and exported?

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4-(Boc-amino)benzylamine is carefully packed to ensure stability during transit and is available for global export by Tech Serve Solutions. Specific packaging details can be provided upon request.

How can I request a sample or quote for 4-(Boc-amino)benzylamine?

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To request a sample or a quote for 4-(Boc-amino)benzylamine, please contact our sales team through the website or by phone. Provide your specific requirements, and we will assist you promptly.

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