4-(Boc-amino)benzylamine
4-(Boc-amino)benzylamine (CAS: 220298-96-4) is an organic compound with the molecular formula C12H18N2O2 and a molecular weight of 222.28 g/mol. This molecule features a tert-butyl carbamate protecting group on the amine functionality, making it a valuable intermediate in organic synthesis. It is commonly employed as a building block in the preparation of more complex molecules, particularly within the pharmaceutical and fine chemical sectors.
- IUPAC
- (4-Aminomethyl-phenyl)-carbamic acid tert-butyl ester,4-(Aminomethyl)-N-Boc-aniline,tert-Butyl N-[4-(aminomethyl)phenyl]carbamate
- Synonyms
- tert-Butyl N-[4-(aminomethyl)phenyl]carbamate(4-Aminomethyl-phenyl)-carbamic acid tert-butyl ester4-(Aminomethyl)-N-Boc-aniline

Pharmaceutical Intermediate
Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs). Its protected amine and reactive benzylamine functionalities allow for selective derivatization in multi-step synthetic routes.
Organic Synthesis Reagent
Utilised in academic and industrial research laboratories for the construction of novel organic compounds. It is particularly useful for introducing protected aminobenzyl moieties into target molecules.
Peptide Synthesis
Can be incorporated into peptide chains or used in the synthesis of peptide mimetics, leveraging its amine and benzyl functionalities for linkage and modification.
Material Science
Potential applications in the development of novel polymers or functional materials where the aminobenzyl structure can impart specific properties.
| Molecular weight | 222.28 |
|---|---|
| Empirical formula | C12H18N2O2 |
| Assay | 95% |
| Melting point | 107-113 °C |

Hazard statements
- H302Harmful if swallowed
- H317May cause an allergic skin reaction
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-43 |
| Safety statements (S) | 36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-(Boc-amino)benzylamine used for?
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4-(Boc-amino)benzylamine is primarily used as a building block in organic synthesis, particularly in the preparation of pharmaceutical intermediates and other complex organic molecules. Its protected amine and reactive benzylamine groups offer versatility in synthetic strategies.
What is the CAS number and molecular formula for 4-(Boc-amino)benzylamine?
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The CAS number for 4-(Boc-amino)benzylamine is 220298-96-4, and its molecular formula is C12H18N2O2.
What grade and purity does Tech Serve Solutions supply for 4-(Boc-amino)benzylamine?
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Tech Serve Solutions supplies 4-(Boc-amino)benzylamine with an assay of 95%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 4-(Boc-amino)benzylamine be handled safely?
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4-(Boc-amino)benzylamine is classified with a GHS07 symbol and a 'Warning' signal word. It carries hazard statements H302 (Harmful if swallowed) and H317 (May cause an allergic skin reaction). Handle with appropriate personal protective equipment, including gloves and protective clothing, and avoid ingestion and skin contact. Please refer to the Safety Data Sheet (SDS) for comprehensive handling information.
How is 4-(Boc-amino)benzylamine packed and exported?
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4-(Boc-amino)benzylamine is carefully packed to ensure stability during transit and is available for global export by Tech Serve Solutions. Specific packaging details can be provided upon request.
How can I request a sample or quote for 4-(Boc-amino)benzylamine?
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To request a sample or a quote for 4-(Boc-amino)benzylamine, please contact our sales team through the website or by phone. Provide your specific requirements, and we will assist you promptly.
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