4-(Chloroacetyl)morpholine
4-(Chloroacetyl)morpholine (CAS 1440-61-5) is a heterocyclic organic compound with the molecular formula C6H10ClNO2 and a molecular weight of 163.60 g/mol. This chemical serves as a valuable intermediate and building block in organic synthesis, particularly within the pharmaceutical and fine chemical industries. Its structure, featuring a morpholine ring and a chloroacetyl group, enables diverse chemical transformations.
- IUPAC
- 2-Chloro-1-(4-morpholinyl)ethanone,2-Chloro-1-morpholinoethanone,2-Morpholino-2-oxoethyl chloride,4-Morpholinylcarbonylmethyl chloride,N-(Chloroacetyl)morpholine,Chloroacetic acid morpholide,Chloroacetic acid morpholine amide,Morpholine chloroacetamide
- Synonyms
- 2-Chloro-1-(4-morpholinyl)ethanone2-Chloro-1-morpholinoethanone2-Morpholino-2-oxoethyl chloride4-Morpholinylcarbonylmethyl chlorideN-(Chloroacetyl)morpholineChloroacetic acid morpholideChloroacetic acid morpholine amideMorpholine chloroacetamide
Pharmaceutical Intermediate
Utilised in the synthesis of active pharmaceutical ingredients (APIs). The chloroacetyl functionality allows for facile nucleophilic substitution reactions to build more complex molecular structures.
Organic Synthesis Building Block
Serves as a versatile reagent in general organic synthesis, enabling the introduction of the morpholine moiety into various organic molecules. Suitable for constructing heterocyclic compounds.
Research and Development
Employed in laboratory settings for exploring novel synthetic pathways and developing new chemical entities. Its reactivity makes it a useful tool for medicinal chemistry research.
| Molecular weight | 163.60 |
|---|---|
| Empirical formula | C6H10ClNO2 |
| Assay | 97% |
| Density | 1.257 g/mL at 25 °C |
| Refractive index | n20/D 1.512 |
| Melting point | 26-30 °C |
Hazard statements
- H302Harmful if swallowed
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | >110 °C / >230 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-(Chloroacetyl)morpholine used for?
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4-(Chloroacetyl)morpholine is primarily used as an intermediate and building block in organic synthesis, particularly for pharmaceuticals and fine chemicals, and in research and development laboratories.
What is the CAS number and formula for 4-(Chloroacetyl)morpholine?
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The CAS number is 1440-61-5 and the empirical formula is C6H10ClNO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-(Chloroacetyl)morpholine with an assay of 97%. This product is not represented as USP, BP, EP, or pharmacopoeia grade.
What are the primary hazards associated with 4-(Chloroacetyl)morpholine?
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4-(Chloroacetyl)morpholine is classified as harmful if swallowed (H302) and causes serious eye irritation (H319). Appropriate personal protective equipment, including eyeshields, gloves, and suitable respiratory protection, should be used during handling.
How is 4-(Chloroacetyl)morpholine packed, shipped, and exported?
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4-(Chloroacetyl)morpholine is carefully packed to ensure safe transit and is exported globally by Tech Serve Solutions in compliance with international shipping regulations.
How can I request a sample or quote for 4-(Chloroacetyl)morpholine?
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To request a sample or a quote for 4-(Chloroacetyl)morpholine, please contact our sales team via the website or direct inquiry channels.
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