4-Bromo-2-fluorophenylboronic acid
4-Bromo-2-fluorophenylboronic acid (CAS: 216393-64-5) is an organoboron compound with the molecular formula C6H5BBrFO2 and a molecular weight of 218.82 g/mol. This disubstituted aryl boronic acid is a valuable building block in organic synthesis. It is frequently employed in Suzuki-Miyaura cross-coupling reactions for the construction of complex organic molecules, particularly in the development of pharmaceuticals and advanced materials.
- Synonyms
- 4-bromo-2-fluorobenzeneboronic acid
Suzuki-Miyaura Cross-Coupling Reagent
Utilised as a key coupling partner in palladium-catalysed Suzuki-Miyaura reactions to form new carbon-carbon bonds. This enables the synthesis of biaryl compounds and other complex structures.
Pharmaceutical Intermediate
Serves as a crucial building block in the synthesis of active pharmaceutical ingredients (APIs). Its structure allows for the introduction of specific aryl and fluoro-aryl moieties into drug candidates.
Materials Science
Incorporated into the synthesis of organic electronic materials, such as organic light-emitting diodes (OLEDs) and organic photovoltaics (OPVs), due to the influence of the fluorine and bromine substituents on electronic properties.
Agrochemical Research
Applied in the discovery and development of new agrochemicals, where specific aryl structures are required for biological activity.
| Molecular weight | 218.82 |
|---|---|
| Empirical formula | C6H5BBrFO2 |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Bromo-2-fluorophenylboronic acid used for?
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4-Bromo-2-fluorophenylboronic acid is primarily used as a building block in organic synthesis, particularly for Suzuki-Miyaura cross-coupling reactions to create complex molecules for pharmaceutical, agrochemical, and materials science applications.
What is the CAS number and molecular formula?
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The CAS number for 4-Bromo-2-fluorophenylboronic acid is 216393-64-5, and its empirical formula is C6H5BBrFO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Bromo-2-fluorophenylboronic acid typically as a research or technical grade with high purity. We do not represent this product as USP, BP, or EP grade. Please refer to the product's specification sheet for exact details.
How should 4-Bromo-2-fluorophenylboronic acid be handled?
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Refer to the Safety Data Sheet (SDS) for detailed hazard information and handling precautions. Generally, it should be handled in a well-ventilated area, avoiding contact with skin, eyes, and clothing. Appropriate personal protective equipment (PPE) should be worn.
Is this chemical suitable for pharmaceutical manufacturing?
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While it is a valuable intermediate in pharmaceutical research and synthesis, its suitability for specific GMP manufacturing processes depends on the required grade and regulatory approval, which should be confirmed with your quality assurance team. Tech Serve Solutions provides it for research and development purposes.
How is this chemical shipped and exported?
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Tech Serve Solutions safely packages and exports 4-Bromo-2-fluorophenylboronic acid globally, adhering to all relevant international shipping and customs regulations for chemical substances.
How can I request a quote or sample?
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To request a quote or sample of 4-Bromo-2-fluorophenylboronic acid, please use the 'Request Quote' or 'Request Sample' function on our website, or contact our sales team directly.
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