4-Bromo-2-fluorophenylzinc iodide solution
4-Bromo-2-fluorophenylzinc iodide solution (CAS: 352530-44-0, Formula: BrC6H3(F)ZnI) is a highly reactive organozinc halide reagent. With a molecular weight of 366.28 g/mol, it is supplied as a 0.5 M solution in THF. This compound is crucial in organic synthesis for introducing the 4-bromo-2-fluorophenyl moiety through various cross-coupling reactions, enabling the construction of complex molecular architectures.
Organometallic Cross-Coupling Reactions
Utilised in Negishi and related cross-coupling reactions to form new carbon-carbon bonds. It enables the selective introduction of the 4-bromo-2-fluorophenyl group onto other organic molecules.
Synthesis of Pharmaceutical Intermediates
Serves as a key building block in the multi-step synthesis of complex organic molecules, including potential pharmaceutical intermediates. Its specific functionalization allows for precise manipulation in drug discovery programmes.
Development of Functional Materials
Can be employed in the synthesis of novel organic materials where the specific electronic and structural properties of the fluorinated aryl group are desired. Facilitates the creation of specialised polymers and electronic components.
| Molecular weight | 366.28 |
|---|---|
| Linear formula | BrC6H3(F)ZnI |
| Boiling point | 65 °C |
| Density | 1.016 g/mL at 25 °C |
| Concentration | 0.5 M in THF |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P281Use personal protective equipment as required
- P305IF IN EYES
| Flash point | -17 °C / 1.4 °F |
|---|---|
| Transport (UN / ADR) | UN 2056 3 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-19-36/37-40 |
| Safety statements (S) | 16-26-36/37 |
| Supplemental hazards | May form explosive peroxides. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Bromo-2-fluorophenylzinc iodide solution used for?
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4-Bromo-2-fluorophenylzinc iodide solution is primarily used in organometallic cross-coupling reactions, such as Negishi coupling, for the synthesis of complex organic molecules, including pharmaceutical intermediates and functional materials.
What is the CAS number and chemical formula?
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The CAS number for 4-Bromo-2-fluorophenylzinc iodide solution is 352530-44-0, and its chemical formula is BrC6H3(F)ZnI.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Bromo-2-fluorophenylzinc iodide solution as a 0.5 M solution in THF. TSS does not represent this product as USP, BP, EP, or other pharmacopoeia grades.
How should 4-Bromo-2-fluorophenylzinc iodide solution be handled and stored?
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This compound is flammable (H225), causes serious eye irritation (H319), and may cause respiratory irritation (H335), and is suspected of causing cancer (H351). It may form explosive peroxides. Store refrigerated at 2-8°C and keep away from heat, sparks, and open flames. Handle under an inert atmosphere.
Is this product eligible for international export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals and can export 4-Bromo-2-fluorophenylzinc iodide solution. Please contact us for specific shipping and regulatory information.
How can I request a sample or quote?
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To request a sample or a quotation for 4-Bromo-2-fluorophenylzinc iodide solution, please visit the Tech Serve Solutions website or contact our sales department directly.
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