4-Bromo-2-fluoropyridine
4-Bromo-2-fluoropyridine (CAS: 128071-98-7) is a halogenated heterocyclic compound with the molecular formula C5H3BrFN and a molecular weight of 175.99 g/mol. As a fluorinated pyridine derivative, it serves as a versatile building block in organic synthesis. Its primary applications lie in the development of novel pharmaceuticals and agrochemicals, leveraging the unique reactivity conferred by the bromine and fluorine substituents.

Pharmaceutical Intermediate
Utilised in the synthesis of active pharmaceutical ingredients (APIs) and drug discovery programs. The pyridine core and halogen substituents allow for diverse functionalisation strategies in medicinal chemistry.
Agrochemical Development
Serves as a key intermediate in the creation of new pesticides, herbicides, and fungicides. The presence of fluorine can enhance the efficacy and metabolic stability of agrochemical compounds.
Organic Synthesis Building Block
A valuable reagent for introducing the 2-fluoropyridinyl moiety into complex organic molecules. Its reactivity profile makes it suitable for cross-coupling reactions and other transformations.
Material Science Research
Explored for potential use in the development of advanced materials, where its electronic and structural properties might be beneficial.
| Molecular weight | 175.99 |
|---|---|
| Empirical formula | C5H3BrFN |
| Assay | 97% |
| Density | 1.713 g/mL at 25 °C |
| Refractive index | n20/D 1.531 |


Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Flash point | 71 °C / 159.8 °F |
|---|---|
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-37/38-41 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Bromo-2-fluoropyridine used for?
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4-Bromo-2-fluoropyridine is primarily used as a building block in organic synthesis, particularly for the development of pharmaceuticals and agrochemicals. It is also utilised in material science research.
What are the CAS number and formula for 4-Bromo-2-fluoropyridine?
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The CAS number is 128071-98-7, and the empirical formula is C5H3BrFN.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Bromo-2-fluoropyridine with an assay of 97%. This is a technical/research grade material, and we do not represent it as USP, BP, or EP.
How should 4-Bromo-2-fluoropyridine be handled safely?
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4-Bromo-2-fluoropyridine is classified as Danger, with hazards including H302 (Harmful if swallowed), H315 (Causes skin irritation), H318 (Causes serious eye damage), and H335 (May cause respiratory irritation). Handle with appropriate personal protective equipment in a well-ventilated area. Refer to the Safety Data Sheet for comprehensive handling instructions.
Is 4-Bromo-2-fluoropyridine a controlled substance?
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The provided data does not indicate that 4-Bromo-2-fluoropyridine is a controlled substance.
How is 4-Bromo-2-fluoropyridine packed and shipped?
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4-Bromo-2-fluoropyridine is shipped according to relevant transport regulations, identified as NA 1993, Packing Group III. Specific packaging details are available upon request.
How can I request a sample or quote for 4-Bromo-2-fluoropyridine?
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To request a sample or a quote, please contact our sales department through the website or by phone, providing your specific requirements.
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