2,6-Dimethoxybenzoyl chloride
2,6-Dimethoxybenzoyl chloride (CAS 1989-53-3) is an organic compound with the molecular formula (CH₃O)₂C₆H₃COCl and a molecular weight of 200.62 g/mol. As an acid halide and carbonyl compound, it serves as a valuable building block in organic synthesis. It is primarily used as an intermediate in the preparation of more complex molecules, particularly in research and development settings for novel compound synthesis.
- Synonyms
- (CH3O)2C6H3COCl

Synthesis of Penicillin Derivatives
2,6-Dimethoxybenzoyl chloride has been employed in the synthetic pathways for specific penicillin derivatives, such as 2,6-dimethoxyphenylpenicillin. This application highlights its utility in medicinal chemistry research.
Preparation of Natural Product Analogues
This compound has been utilized in the preparation of didechloro-<i>OO</i>-dimethylpyoluteorin, indicating its role in the synthesis of natural product analogues and related research.
Organic Synthesis Building Block
As a reactive acid chloride, 2,6-Dimethoxybenzoyl chloride functions as a versatile building block in general organic synthesis, enabling the introduction of the 2,6-dimethoxybenzoyl moiety into various molecular structures.
| Molecular weight | 200.62 |
|---|---|
| Linear formula | (CH3O)2C6H3COCl |
| Assay | 80% |
| Application | 2,6-Dimethoxybenzoyl chloride has been used in the preparation of:• 2,6-dimethoxyphenylpenicillin1• didechloro-OO-dimethylpyoluteorin2 |
| Melting point | 64-66 °C(lit.) |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-27-28-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,6-Dimethoxybenzoyl chloride used for?
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2,6-Dimethoxybenzoyl chloride is used as a building block in organic synthesis, notably in the preparation of compounds such as 2,6-dimethoxyphenylpenicillin and didechloro-<i>OO</i>-dimethylpyoluteorin.
What are the CAS number and formula for 2,6-Dimethoxybenzoyl chloride?
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The CAS number for 2,6-Dimethoxybenzoyl chloride is 1989-53-3, and its linear formula is (CH₃O)₂C₆H₃COCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,6-Dimethoxybenzoyl chloride with a minimum assay of 80%. This product is supplied for research and industrial purposes; TSS does not represent it as USP, BP, EP, or other pharmacopoeial grades.
How should 2,6-Dimethoxybenzoyl chloride be handled safely?
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2,6-Dimethoxybenzoyl chloride is a corrosive substance (GHS05, Danger, H314). Handle with appropriate personal protective equipment, including eyeshields, face shields, and chemical-resistant gloves. Ensure adequate ventilation or use a respirator.
Is 2,6-Dimethoxybenzoyl chloride a controlled substance?
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The provided data does not indicate that 2,6-Dimethoxybenzoyl chloride is a controlled substance.
How is 2,6-Dimethoxybenzoyl chloride shipped and exported?
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2,6-Dimethoxybenzoyl chloride is shipped and exported according to relevant dangerous goods regulations, identified as UN 3261, Class 8, Packing Group II.
How can I request a sample or quote for 2,6-Dimethoxybenzoyl chloride?
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To request a sample or a quote for 2,6-Dimethoxybenzoyl chloride, please contact the Tech Serve Solutions sales team through the website or by phone.
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