Cyclooctanone

CAS 502-49-8C8H14(=O)Chemical Synthesis

Cyclooctanone (CAS: 502-49-8), with the molecular formula C8H14(=O) and a molecular weight of 126.20 g/mol, is a cyclic ketone. This compound is primarily utilised as a versatile building block in organic synthesis. It serves as a key intermediate for the preparation of various complex molecules, including sulfonylbicycloalkanols and lactones, underscoring its importance in chemical research and development.

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Cyclooctanone (C8H14(=O)) — chemical structure, CAS 502-49-8; Chemistry, fine chemical supplied by Tech Serve Solutions

Building BlocksC7 to C8Carbonyl CompoundsChemical SynthesisKetones

01 /Applications

Synthesis of Sulfonylbicycloalkanols

Cyclooctanone is employed in the preparation of sulfonylbicyclo[3.2.0]heptan-1-ols, sulfonylbicyclo[5.2.0]nonan-1-ols, and sulfonylbicyclo[6.2.0]decan-1-ols, facilitating the creation of novel cyclic structures.

Preparation of Lactones

This ketone serves as a precursor in the synthesis of 14-membered lactones, a class of compounds significant in various fields of chemistry.

Organic Building Block

As a C7 to C8 carbonyl compound and ketone, cyclooctanone functions as a fundamental building block in organic synthesis, enabling the construction of more complex molecular architectures.

02 /Properties

Molecular weight	126.20
Linear formula	C8H14(=O)
Assay	≥95.0% (GC)
Grade	purum
Boiling point	195-197 °C(lit.)
Density	0.958 g/mL at 25 °C(lit.)
Solubility	methanol: soluble1 g/10 mL, clear to very faintly turbid, colorless
Melting point	32-41 °C(lit.)
Application	Cyclooctanone has been used in the preparation of:• sulfonylbicyclo[3.2.0]heptan-1-ols, sulfonylbicyclo[5.2.0]-nonan-1-ols and sulfonylbicyclo[6.2.0]decan-1-ols1• 14-membered lactones2

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust, fume, gas or vapours
P305IF IN EYES

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Flash point	73 °C / 163.4 °F
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xi
Risk statements (R)	36/37/38-52/53
Safety statements (S)	26-61

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

502-49-8

MDL number

MFCD00001754

PubChem substance

24857844

Beilstein registry

1280738

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Cyclooctanone used for?

Cyclooctanone is used as a building block in chemical synthesis, notably in the preparation of sulfonylbicycloalkanols and 14-membered lactones.

What is the CAS number and formula for Cyclooctanone?

The CAS number for Cyclooctanone is 502-49-8, and its linear formula is C8H14(=O).

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Cyclooctanone with a purity of ≥95.0% (GC), designated as purum grade. We do not represent this product as USP, BP, or EP grade.

How should Cyclooctanone be handled safely?

Cyclooctanone is classified with GHS07 symbol and 'Warning' signal word, carrying hazard statements H315, H319, and H335. It can cause skin irritation, serious eye irritation, and respiratory irritation. Recommended personal protective equipment includes eyeshields, gloves, and a type N95 (US) or P1 (EN143) respirator filter. Always consult the Safety Data Sheet (SDS) before handling.

Is Cyclooctanone a controlled substance?

The provided data does not indicate that Cyclooctanone (CAS: 502-49-8) is a controlled substance.

How is Cyclooctanone packed and exported by TSS?

Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. Specific packing and export details for Cyclooctanone can be provided upon request.