Cycloleucine

CAS 52-52-8H2NC5H8CO2HChemical Synthesis

Cycloleucine (CAS: 52-52-8), with the linear formula H2NC5H8CO2H and a molecular weight of 129.16 g/mol, is a cyclic unnatural amino acid derivative. It is recognised for its role in chemical biology and peptide chemistry. TSS supplies Cycloleucine with a purity of ≥97.0% (NT), suitable for research and synthesis applications.

IUPAC: 1-Aminocyclopentanecarboxylic acid
Synonyms: 1-Aminocyclopentanecarboxylic acid

Email us

Cycloleucine (H2NC5H8CO2H) — chemical structure, CAS 52-52-8; Chemistry, fine chemical supplied by Tech Serve Solutions

Chemical BiologyChemical SynthesisLeucine DerivativesPeptide Chemistry

01 /Applications

Chemical Synthesis

Cycloleucine serves as a valuable building block in the synthesis of novel organic compounds and complex molecules. Its unique cyclic structure allows for specific stereochemical outcomes in synthetic pathways.

Peptide Chemistry

This unnatural amino acid can be incorporated into peptides to modify their structure, stability, and biological activity. It is used in the design of peptidomimetics and modified peptides for research purposes.

Chemical Biology Research

Cycloleucine is employed as a tool in chemical biology to probe biological systems and understand enzyme mechanisms. Its structural similarity to natural amino acids but with distinct properties makes it useful for studying protein interactions.

02 /Properties

Molecular weight	129.16
Linear formula	H2NC5H8CO2H
Assay	≥97.0% (NT)
Melting point	320 °C (dec.)(lit.)

03 /Safety & handling

GHS hazard pictogram: Toxic (GHS06) — Toxic

Danger

Hazard statements

H301Toxic if swallowed

Precautionary statements

P301IF SWALLOWED

Protective equipment	dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Transport (UN / ADR)	UN 2811 6.1 / PGIII
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xn
Risk statements (R)	22
Safety statements (S)	22-24/25

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

52-52-8

MDL number

MFCD00001381

PubChem substance

24890914

Beilstein registry

636626

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Cycloleucine used for?

Cycloleucine is used in chemical synthesis, peptide chemistry, and chemical biology research. It functions as a building block for novel compounds and as a tool for probing biological systems.

What are the CAS number and formula for Cycloleucine?

The CAS number for Cycloleucine is 52-52-8 and its linear formula is H2NC5H8CO2H.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Cycloleucine with a purity of ≥97.0% (NT). We do not represent this product as USP, BP, EP, or pharmaceutical grade.

How should Cycloleucine be handled safely?

Cycloleucine is classified as toxic if swallowed (H301). Handle with appropriate personal protective equipment including a dust mask (N95 type), eyeshields, faceshields, and gloves. Avoid breathing dust. It is classified under hazard codes Xn in Europe with risk statement R22.

How is Cycloleucine packed and shipped?

Cycloleucine is shipped as UN 2811, Class 6.1, Packing Group III. Please refer to our shipping policy for international export details.

How can I request a sample or quote for Cycloleucine?

To request a sample or obtain a quote for Cycloleucine, please use the contact form on our website or email our sales department with your requirements.