4-Amino-3-methoxybenzoic acid
4-Amino-3-methoxybenzoic acid (CAS 2486-69-3), with the molecular formula H2NC6H3(OCH3)CO2H and a molecular weight of 167.16 g/mol, is a key aromatic amino acid derivative. This compound serves as a vital building block in organic synthesis. Notably, it is employed in the efficient synthesis of carbazole alkaloids such as mukonine and mukonidine through oxidative annulation processes, highlighting its importance in complex molecule construction.

Carbazole Alkaloid Synthesis
4-Amino-3-methoxybenzoic acid is a critical intermediate for the synthesis of carbazole alkaloids like mukonine and mukonidine. Its structure facilitates oxidative annulation reactions, enabling the formation of these complex natural products.
Chemical Synthesis Building Block
As a functionalised aromatic molecule, it is valuable in various chemical synthesis pathways. The presence of amino, methoxy, and carboxylic acid groups allows for diverse chemical transformations.
Research and Development
This compound is utilized in research settings for exploring novel synthetic methodologies and developing new chemical entities, particularly within the fields of chemical biology and peptide chemistry.
| Molecular weight | 167.16 |
|---|---|
| Linear formula | H2NC6H3(OCH3)CO2H |
| Assay | 98% |
| Application | Key building block for the efficient synthesis of carbazole alkaloids mukonine and mukonidine via oxidative annulation.1 |
| Melting point | 186-188 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Amino-3-methoxybenzoic acid primarily used for?
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It is primarily used as a key building block in the synthesis of carbazole alkaloids, such as mukonine and mukonidine, via oxidative annulation. It also serves as a general intermediate in chemical synthesis.
What are the CAS number and molecular formula for 4-Amino-3-methoxybenzoic acid?
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The CAS number is 2486-69-3, and the molecular formula is H2NC6H3(OCH3)CO2H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Amino-3-methoxybenzoic acid with an assay of 98%. We do not represent this product as USP, BP, EP, or any other pharmacopoeial grade.
How should 4-Amino-3-methoxybenzoic acid be handled safely?
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Handle with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. Avoid breathing dust and ensure adequate ventilation. Refer to the safety data sheet for comprehensive handling instructions. This compound is a warning irritant to skin, eyes, and respiratory tract.
How is 4-Amino-3-methoxybenzoic acid packed, shipped, and exported?
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We ensure that 4-Amino-3-methoxybenzoic acid is packed securely in compliance with all relevant transport regulations. We are experienced in exporting fine chemicals globally.
How can I request a quote or sample for 4-Amino-3-methoxybenzoic acid?
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Please contact our sales team or use the online request form on our website to inquire about pricing, bulk quantities, or to request a sample of 4-Amino-3-methoxybenzoic acid.
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