4-Amino-3-methylbenzoic acid
4-Amino-3-methylbenzoic acid (CAS: 2486-70-6; Formula: H2NC6H3(CH3)CO2H; MW: 151.16) is a substituted benzoic acid derivative. This aromatic compound functions as a key building block in organic synthesis, particularly within chemical biology and peptide chemistry. It serves as a valuable intermediate for constructing more complex molecules, including unnatural amino acid derivatives, and is utilized in various chemical research and development applications.

Organic Synthesis Intermediate
4-Amino-3-methylbenzoic acid is frequently employed as a versatile intermediate in the synthesis of complex organic molecules. Its structure allows for diverse chemical transformations, making it useful in the development of new compounds.
Chemical Biology Research
This compound finds application in chemical biology, where it can be incorporated into probes or modified biomolecules to study biological processes. It serves as a component for exploring molecular interactions and functions.
Peptide Chemistry
Within peptide chemistry, 4-Amino-3-methylbenzoic acid can be utilized to create modified peptides or unnatural amino acid derivatives. This enables the study of peptide structure-activity relationships and the development of novel peptide-based therapeutics.
Development of Unnatural Amino Acids
The compound is instrumental in the synthesis of unnatural amino acid derivatives. These modified amino acids are crucial for expanding the functional scope of peptides and proteins in research and biotechnological applications.
| Molecular weight | 151.16 |
|---|---|
| Linear formula | H2NC6H3(CH3)CO2H |
| Assay | 98% |
| Melting point | 169-171 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Amino-3-methylbenzoic acid used for?
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4-Amino-3-methylbenzoic acid is used as an intermediate in organic synthesis, chemical biology, peptide chemistry, and for the development of unnatural amino acid derivatives.
What is the CAS number and chemical formula for 4-Amino-3-methylbenzoic acid?
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The CAS number is 2486-70-6 and the linear chemical formula is H2NC6H3(CH3)CO2H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Amino-3-methylbenzoic acid with an assay of 98%. This product is not supplied as USP, BP, EP, or pharmaceutical grade.
What are the primary hazards associated with 4-Amino-3-methylbenzoic acid?
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4-Amino-3-methylbenzoic acid is classified with the signal word 'Warning' and has hazard statements H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Appropriate personal protective equipment including a dust mask, eyeshields, and gloves should be used when handling.
How is 4-Amino-3-methylbenzoic acid packed and exported?
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Tech Serve Solutions, a global supplier and exporter since 1998, ensures products are appropriately packaged for safe domestic and international shipment.
How can I request a quote or sample for 4-Amino-3-methylbenzoic acid?
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To request a quote or sample, please contact the Tech Serve Solutions sales team through our website or by phone.
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