4-Amino-3-methylphenol
4-Amino-3-methylphenol (CAS: 2835-99-6), with the molecular formula H2NC6H3(CH3)OH and a molar mass of 123.15 g/mol, is an organic building block. This phenol derivative serves as a valuable intermediate in chemical synthesis. It is primarily utilised in the development of novel molecular structures, such as specific tweezer-molecules designed for targeted binding interactions through intramolecular hydrogen bonding.
- IUPAC
- 2-Amino-5-hydroxytoluene,4-Hydroxy-2-methylaniline,4-Amino-m-cresol
- Synonyms
- 2-Amino-5-hydroxytoluene4-Hydroxy-2-methylaniline4-Amino-m-cresol
Synthesis of Tweezer-Molecules
4-Amino-3-methylphenol has been employed in the synthesis of specialised tweezer-molecules. These molecules are engineered to exhibit a preferred binding conformation, facilitated by intramolecular hydrogen bonding.
Organic Synthesis Intermediate
As an organic building block, this compound is suitable for various chemical synthesis pathways. Its structure, featuring both an amino group and a hydroxyl group on a substituted benzene ring, allows for diverse functionalisation.
Research and Development
The compound finds application in research settings for the exploration of new chemical entities and reaction methodologies. Its utility is documented in the creation of complex molecular architectures.
| Molecular weight | 123.15 |
|---|---|
| Linear formula | H2NC6H3(CH3)OH |
| Assay | ≥98.0% (NT) |
| Application | 4-Amino-3-methylphenol was used in synthesis of a new type of tweezer-molecule in which a strongly preferred binding conformation is generated by convergent, intramolecular hydrogen bonding1. |
| Melting point | 176-179 °C(lit.)177-179 °C |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Amino-3-methylphenol used for?
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4-Amino-3-methylphenol is used as a chemical intermediate in organic synthesis, notably for creating novel structures like tweezer-molecules designed for specific binding conformations.
What is the CAS number and chemical formula for 4-Amino-3-methylphenol?
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The CAS number is 2835-99-6, and its chemical formula is H2NC6H3(CH3)OH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Amino-3-methylphenol with an assay of ≥98.0% (NT). We do not represent this product as USP, BP, or EP grade.
How should 4-Amino-3-methylphenol be handled?
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Handling requires caution due to its hazards (H302, H315, H319, H335). Use appropriate personal protective equipment including a dust mask (N95), eyeshields, and gloves. Ensure adequate ventilation.
Is 4-Amino-3-methylphenol exported by Tech Serve Solutions?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 4-Amino-3-methylphenol.
How can I request a quote or sample?
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Please contact our sales team via the website or direct inquiry channels to request a quote or sample of 4-Amino-3-methylphenol.
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