4-Amino-3-fluorophenylboronic acid hydrochloride
4-Amino-3-fluorophenylboronic acid hydrochloride (CAS: 1256355-32-4) is a valuable organoboron compound with the molecular formula C6H8BClFNO2 and a molecular weight of 191.40 g/mol. This disubstituted aryl boronic acid is an important building block in organic synthesis, particularly in cross-coupling reactions. It finds application in the development of pharmaceuticals and advanced materials, offering a reactive handle for introducing fluorinated aminophenyl moieties into complex molecular architectures.
Suzuki-Miyaura Cross-Coupling Reactions
Serves as a key reagent in Suzuki-Miyaura cross-coupling reactions for the formation of carbon-carbon bonds. This enables the synthesis of biaryl compounds and other complex organic structures.
Pharmaceutical Intermediate
Utilised in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates. Its fluorinated aminophenyl structure is often incorporated into molecules with potential therapeutic activity.
Materials Science
Employed in the development of novel materials, including organic light-emitting diodes (OLEDs) and functional polymers, where its specific electronic and structural properties can be advantageous.
Organic Synthesis Building Block
A versatile intermediate for constructing complex organic molecules. The boronic acid functionality allows for diverse synthetic transformations beyond cross-coupling.
| Molecular weight | 191.40 |
|---|---|
| Empirical formula | C6H8BClFNO2 |
| Storage temperature | 2-8°C |
| Melting point | 150-160 °C |
Hazard statements
- H302Harmful if swallowed
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Amino-3-fluorophenylboronic acid hydrochloride primarily used for?
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It is primarily used as a building block in organic synthesis, particularly for Suzuki-Miyaura cross-coupling reactions, and as an intermediate in the development of pharmaceuticals and advanced materials.
What is the CAS number and molecular formula for this compound?
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The CAS number is 1256355-32-4 and the molecular formula is C6H8BClFNO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product for research and development purposes. The specific assay and purity are available upon request or on the Certificate of Analysis. We do not represent this product as USP, BP, EP, or any other pharmacopoeial grade unless explicitly stated.
What are the safety and handling precautions for this chemical?
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This compound is classified as harmful if swallowed (H302) and carries a 'Warning' signal word. Handle with appropriate personal protective equipment, including gloves and eye protection, in a well-ventilated area to avoid ingestion and inhalation. Store at 2-8°C.
How is 4-Amino-3-fluorophenylboronic acid hydrochloride packed and shipped?
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Tech Serve Solutions packs and ships chemicals globally, adhering to all relevant transportation regulations for hazardous materials. Packaging is designed to maintain product integrity and safety during transit.
How can I request a sample or a quote for this product?
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To request a sample or a quote, please contact our sales team through the website or by calling us directly. Please reference the product name and CAS number (1256355-32-4).
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