(3R,4R)-(−)-1-Benzyl-3,4-pyrrolidinediol
(3R,4R)-(−)-1-Benzyl-3,4-pyrrolidinediol (CAS: 163439-82-5) is a chiral heterocyclic building block with the molecular formula C11H15NO2 and a molecular weight of 193.24 g/mol. This enantiomerically pure compound serves as a valuable intermediate in asymmetric synthesis and complex chemical manufacturing. Its defined stereochemistry makes it essential for the stereoselective construction of target molecules in pharmaceutical research and fine chemical production.
- Synonyms
- 163439-82-5C11H15NO2

Chiral Building Block
Utilised in the stereoselective synthesis of complex organic molecules, particularly where precise control over chirality is critical for biological activity or material properties.
Asymmetric Synthesis
Serves as a key intermediate in enantioselective transformations, enabling the creation of chiral centres with high optical purity in target compounds.
Pharmaceutical Intermediates
A fundamental component in the multi-step synthesis pathways for active pharmaceutical ingredients (APIs), contributing to the development of novel therapeutics.
Heterocyclic Chemistry
Incorporated into synthetic routes requiring the construction of pyrrolidine ring systems, often found in biologically active natural products and synthetic drugs.
| Molecular weight | 193.24 |
|---|---|
| Empirical formula | C11H15NO2 |
| Assay | ≥97.0% (sum of enantiomers, HPLC) |
| Optical activity | [α]20/D −33.6±3°, c = 1.05% in methanol |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (3R,4R)-(−)-1-Benzyl-3,4-pyrrolidinediol used for?
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This compound is primarily used as a chiral building block in asymmetric synthesis and as an intermediate in the synthesis of complex organic molecules, including potential pharmaceutical agents.
What are the CAS number and formula for (3R,4R)-(−)-1-Benzyl-3,4-pyrrolidinediol?
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The CAS number is 163439-82-5 and the empirical formula is C11H15NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with an assay of ≥97.0% (sum of enantiomers, HPLC). We do not represent this product as USP, BP, or EP grade.
How should (3R,4R)-(−)-1-Benzyl-3,4-pyrrolidinediol be handled?
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Handle with appropriate personal protective equipment, including a dust mask (type N95 US recommended), eyeshields, and gloves. Ensure adequate ventilation as it may cause respiratory irritation (H335).
How is this chemical packed and shipped?
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Tech Serve Solutions exports fine chemicals globally, ensuring appropriate packaging for safe transit according to international regulations. Please contact us for specific export details.
How can I request a sample or quote for this product?
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To request a sample or a quotation, please use the 'Contact Us' form on our website or call our sales department, referencing the product name and CAS number.
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