(3R)-(−)-3-(methyl-1H-indol-3-yl)-3-phenylpropionic acid
(3R)-(−)-3-(methyl-1H-indol-3-yl)-3-phenylpropionic acid (CAS: 406920-67-0, C18H17NO2) is a chiral building block vital for asymmetric synthesis and chemical research. This indole derivative serves as a key intermediate in complex organic synthesis, facilitating the construction of enantiomerically pure compounds. Its precise stereochemistry makes it valuable in developing new pharmaceuticals and advanced materials requiring specific molecular architectures.
Asymmetric Synthesis
Utilized as a chiral precursor to introduce specific stereocenters in target molecules. Its enantiopurity is crucial for the synthesis of optically active compounds.
Pharmaceutical Intermediates
Serves as a building block in the synthesis pathways of active pharmaceutical ingredients (APIs). The indole and phenylpropionic acid moieties offer versatile functionalization points.
Organic Synthesis Research
Employed in academic and industrial research for exploring novel synthetic methodologies and creating complex molecular structures.
Chiral Building Blocks
A valuable component for chemists requiring stereochemically defined starting materials for complex molecular assembly.
| Molecular weight | 279.33 |
|---|---|
| Empirical formula | C18H17NO2 |
| Assay | 97% |
| Optical activity | [α]20/D -44°, c = 1% in chloroform |
| Melting point | 135-139 °C |
Hazard statements
- H301Toxic if swallowed
- H315Causes skin irritation
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
- H334May cause allergy or asthma symptoms if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
- P342
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-36/37/38-42/43 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (3R)-(−)-3-(methyl-1H-indol-3-yl)-3-phenylpropionic acid used for?
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(3R)-(−)-3-(methyl-1H-indol-3-yl)-3-phenylpropionic acid is primarily used in asymmetric synthesis and as a chiral building block for organic synthesis, particularly in the development of pharmaceutical intermediates.
What are the CAS number and molecular formula for this compound?
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The CAS number is 406920-67-0, and the molecular formula is C18H17NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound with an assay of 97%. This product is intended for research and chemical synthesis; we do not represent it as USP, BP, EP, or any other pharmacopoeial grade.
How should (3R)-(−)-3-(methyl-1H-indol-3-yl)-3-phenylpropionic acid be handled?
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This compound is classified as dangerous. It is toxic if swallowed and causes skin and eye irritation. Inhalation may cause respiratory irritation and allergic reactions. Handle with appropriate personal protective equipment including eyeshields, face shields, gloves, and a P2 respirator. Ensure adequate ventilation.
How is this chemical packed, shipped, and exported?
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We ensure secure and compliant packaging for international shipping and export, adhering to all relevant transportation regulations for hazardous materials.
How can I request a sample or quote for this chemical?
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To request a sample or quote, please contact our sales team via the website or provide your details through the product inquiry form.
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