n-Butylboronic acid MIDA ester
n-Butylboronic acid MIDA ester (CAS: 1104637-43-5, C9H16BNO4) is a valuable organometallic reagent within the MIDA boronate class. With a molecular weight of 213.04 g/mol, this compound serves as a versatile building block in organic synthesis, particularly for carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions. Its stable nature, due to the N-methyliminodiacetic acid (MIDA) protecting group, facilitates handling and storage, making it a reliable choice for researchers in medicinal chemistry and materials science.
Suzuki-Miyaura Cross-Coupling Reactions
n-Butylboronic acid MIDA ester is effectively employed as a coupling partner in Suzuki-Miyaura reactions, enabling the synthesis of complex molecules containing the n-butyl moiety. This method is widely used in the pharmaceutical industry for drug discovery and development.
Organic Synthesis Intermediate
As a derivative of boronic acids, this MIDA ester acts as a stable and convenient intermediate for introducing n-butyl groups into organic structures. Its utility spans various synthetic routes requiring precise functionalisation.
Medicinal Chemistry Research
The compound is utilised in the exploration of novel pharmaceutical agents, where the incorporation of specific alkyl chains like n-butyl can modulate a drug candidate's pharmacokinetic and pharmacodynamic properties.
Materials Science Applications
In materials science, n-Butylboronic acid MIDA ester can be a precursor for synthesising specialised polymers and organic electronic materials where precise structural control is essential.
| Molecular weight | 213.04 |
|---|---|
| Empirical formula | C9H16BNO4 |
| Application | Representative Applications of MIDA boronates |
| Melting point | 122-128 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is n-Butylboronic acid MIDA ester used for?
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n-Butylboronic acid MIDA ester is primarily used as a versatile building block in organic synthesis, particularly for Suzuki-Miyaura cross-coupling reactions to introduce n-butyl groups into complex molecules. It finds applications in medicinal chemistry research and materials science.
What is the CAS number and molecular formula?
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The CAS number for n-Butylboronic acid MIDA ester is 1104637-43-5, and its molecular formula is C9H16BNO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies n-Butylboronic acid MIDA ester as a technical or research grade chemical. The specific assay or purity is detailed on the product's Certificate of Analysis. We do not represent this product as USP, BP, or EP grade.
What are the safety precautions for handling n-Butylboronic acid MIDA ester?
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Handling n-Butylboronic acid MIDA ester requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or P1 (EN143) respirator filter is recommended. Please refer to the Safety Data Sheet (SDS) for comprehensive handling and safety information.
How is n-Butylboronic acid MIDA ester packed and shipped?
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n-Butylboronic acid MIDA ester is carefully packed according to industry standards to ensure safe transport and storage. We export globally, adhering to all relevant shipping regulations for chemical compounds.
How can I request a quote or sample?
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To request a quote or a sample of n-Butylboronic acid MIDA ester, please contact our sales team through the provided channels on the Tech Serve Solutions website, detailing your requirements.
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