3-Pyridinecarboxaldehyde
3-Pyridinecarboxaldehyde (CAS: 500-22-1, Formula: C6H5NO, MW: 107.11) is a key heterocyclic aldehyde serving as a versatile building block in organic synthesis. With a purity of 98%, it is commonly employed in the development of pharmaceuticals, agrochemicals, and various fine chemicals. Its reactive aldehyde group and pyridine core make it valuable for creating more complex molecular structures through condensation, reduction, and other synthetic transformations.
- IUPAC
- Nicotinaldehyde
- Synonyms
- Nicotinaldehyde

Pharmaceutical Intermediate
3-Pyridinecarboxaldehyde is frequently used in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates. Its pyridine ring structure is a common motif in many biologically active molecules.
Agrochemical Synthesis
This aldehyde is a valuable precursor for the creation of novel pesticides, herbicides, and fungicides. Its incorporation into molecular structures can impart specific biological activity relevant to crop protection.
Organic Building Block
As a readily available heterocyclic building block, 3-Pyridinecarboxaldehyde is instrumental in academic and industrial research for constructing complex organic molecules and novel chemical entities.
Material Science
It can be utilised in the synthesis of specialty polymers, dyes, and functional materials where its pyridine moiety imparts desired electronic or physical properties.
| Molecular weight | 107.11 |
|---|---|
| Empirical formula | C6H5NO |
| Assay | 98% |
| Boiling point | 78-81 °C/10 mmHg(lit.) |
| Density | 1.141 g/mL at 20 °C(lit.) |
| Refractive index | n20/D 1.549(lit.) |
| Storage temperature | 2-8°C |



Hazard statements
- H226Flammable liquid and vapour
- H302Harmful if swallowed
- H315Causes skin irritation
- H317May cause an allergic skin reaction
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 35 °C / 95 °F |
| Transport (UN / ADR) | UN 1989C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 10-22-37/38-41-43 |
| Safety statements (S) | 26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Pyridinecarboxaldehyde used for?
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3-Pyridinecarboxaldehyde is primarily used as a versatile building block in organic synthesis, particularly for the development of pharmaceuticals, agrochemicals, and fine chemicals. Its reactive aldehyde group and pyridine ring are valuable for creating complex molecular structures.
What is the CAS number and formula for 3-Pyridinecarboxaldehyde?
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The CAS number is 500-22-1 and the empirical formula is C6H5NO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Pyridinecarboxaldehyde with an assay of 98%. We do not represent this product as USP, BP, or EP grade.
How should 3-Pyridinecarboxaldehyde be handled and stored?
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3-Pyridinecarboxaldehyde is flammable (flash point 35 °C) and can cause skin irritation, serious eye damage, and respiratory irritation. It is also harmful if swallowed and may cause an allergic skin reaction. Handle in a well-ventilated area, wear appropriate personal protective equipment including gloves, eye protection, and a respirator. Store at 2-8°C.
Is 3-Pyridinecarboxaldehyde a controlled substance?
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The provided data does not indicate that 3-Pyridinecarboxaldehyde is a controlled substance.
How is this product packed, shipped, and exported?
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3-Pyridinecarboxaldehyde is packed, shipped, and exported in accordance with international regulations for hazardous materials, bearing UN 1989C 3 / PGIII classification.
How can I request a sample or quote for 3-Pyridinecarboxaldehyde?
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To request a sample or quote for 3-Pyridinecarboxaldehyde, please contact our sales team through the website or direct email, providing your specific requirements.
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