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3-Pyridinecarboxaldehyde

CAS 500-22-1C6H5NOChemical Synthesis

3-Pyridinecarboxaldehyde (CAS: 500-22-1, Formula: C6H5NO, MW: 107.11) is a key heterocyclic aldehyde serving as a versatile building block in organic synthesis. With a purity of 98%, it is commonly employed in the development of pharmaceuticals, agrochemicals, and various fine chemicals. Its reactive aldehyde group and pyridine core make it valuable for creating more complex molecular structures through condensation, reduction, and other synthetic transformations.

IUPAC
Nicotinaldehyde
Synonyms
Nicotinaldehyde
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3-Pyridinecarboxaldehyde (C6H5NO) — chemical structure, CAS 500-22-1; Chemistry, fine chemical supplied by Tech Serve Solutions
AldehydesBuilding BlocksC1 to C6Carbonyl CompoundsChemical SynthesisHeterocyclic Building BlocksOrganic Building BlocksPyridines More...
01 /Applications

Pharmaceutical Intermediate

3-Pyridinecarboxaldehyde is frequently used in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates. Its pyridine ring structure is a common motif in many biologically active molecules.

Agrochemical Synthesis

This aldehyde is a valuable precursor for the creation of novel pesticides, herbicides, and fungicides. Its incorporation into molecular structures can impart specific biological activity relevant to crop protection.

Organic Building Block

As a readily available heterocyclic building block, 3-Pyridinecarboxaldehyde is instrumental in academic and industrial research for constructing complex organic molecules and novel chemical entities.

Material Science

It can be utilised in the synthesis of specialty polymers, dyes, and functional materials where its pyridine moiety imparts desired electronic or physical properties.

02 /Properties
Molecular weight107.11
Empirical formulaC6H5NO
Assay98%
Boiling point78-81 °C/10 mmHg(lit.)
Density1.141 g/mL at 20 °C(lit.)
Refractive indexn20/D 1.549(lit.)
Storage temperature2-8°C
03 /Safety & handling
GHS hazard pictogram: Flammable (GHS02)
Flammable
GHS hazard pictogram: Corrosive (GHS05)
Corrosive
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Danger

Hazard statements

  • H226Flammable liquid and vapour
  • H302Harmful if swallowed
  • H315Causes skin irritation
  • H317May cause an allergic skin reaction
  • H318Causes serious eye damage
  • H335May cause respiratory irritation

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P280Wear protective gloves, clothing and eye/face protection
  • P305IF IN EYES
Protective equipmentEyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point35 °C / 95 °F
Transport (UN / ADR)UN 1989C 3 / PGIII
Water hazard class (WGK, DE)3
Hazard codes (EU)Xn
Risk statements (R)10-22-37/38-41-43
Safety statements (S)26-36/37/39

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
500-22-1
MDL number
MFCD00006382
PubChem substance
24898656
Beilstein registry
105343
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 3-Pyridinecarboxaldehyde used for?

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3-Pyridinecarboxaldehyde is primarily used as a versatile building block in organic synthesis, particularly for the development of pharmaceuticals, agrochemicals, and fine chemicals. Its reactive aldehyde group and pyridine ring are valuable for creating complex molecular structures.

What is the CAS number and formula for 3-Pyridinecarboxaldehyde?

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The CAS number is 500-22-1 and the empirical formula is C6H5NO.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies 3-Pyridinecarboxaldehyde with an assay of 98%. We do not represent this product as USP, BP, or EP grade.

How should 3-Pyridinecarboxaldehyde be handled and stored?

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3-Pyridinecarboxaldehyde is flammable (flash point 35 °C) and can cause skin irritation, serious eye damage, and respiratory irritation. It is also harmful if swallowed and may cause an allergic skin reaction. Handle in a well-ventilated area, wear appropriate personal protective equipment including gloves, eye protection, and a respirator. Store at 2-8°C.

Is 3-Pyridinecarboxaldehyde a controlled substance?

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The provided data does not indicate that 3-Pyridinecarboxaldehyde is a controlled substance.

How is this product packed, shipped, and exported?

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3-Pyridinecarboxaldehyde is packed, shipped, and exported in accordance with international regulations for hazardous materials, bearing UN 1989C 3 / PGIII classification.

How can I request a sample or quote for 3-Pyridinecarboxaldehyde?

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To request a sample or quote for 3-Pyridinecarboxaldehyde, please contact our sales team through the website or direct email, providing your specific requirements.

Need 3-Pyridinecarboxaldehyde in a specific grade or volume?