3-Pyridineboronic acid MIDA ester
3-Pyridineboronic acid MIDA ester (CAS: 1257740-56-9; Formula: C10H11BN2O4; MW: 234.02) is a stable, heterocyclic boronate ester. It serves as a valuable building block in organic synthesis, particularly for cross-coupling reactions. This compound finds application in the development of novel pharmaceuticals and agrochemicals, offering a convenient route to introduce the 3-pyridyl moiety.
- IUPAC
- 6-Methyl-2-(3-pyridinyl)-1,3,6,2-dioxazaborocane-4,8-dione

Suzuki-Miyaura Cross-Coupling Reactions
This MIDA ester is an effective coupling partner in Suzuki-Miyaura reactions. It facilitates the formation of carbon-carbon bonds by reacting with aryl or vinyl halides under palladium catalysis, enabling the synthesis of complex biaryl and heteroaryl compounds.
Pharmaceutical Intermediate Synthesis
The 3-pyridyl group is a common structural motif in many biologically active molecules. 3-Pyridineboronic acid MIDA ester allows for the precise and efficient incorporation of this unit into potential drug candidates during medicinal chemistry research and development.
Agrochemical Discovery
This compound can be utilised in the synthesis of novel agrochemicals. Its utility in cross-coupling reactions aids in the construction of complex molecular architectures that may possess herbicidal, fungicidal, or insecticidal properties.
Materials Science
The incorporation of pyridine rings can influence the electronic and photophysical properties of organic materials. This boronate ester serves as a synthon for developing new functional materials with tailored characteristics.
| Molecular weight | 234.02 |
|---|---|
| Empirical formula | C10H11BN2O4 |
| Melting point | 210-217 °C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Pyridineboronic acid MIDA ester primarily used for?
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3-Pyridineboronic acid MIDA ester is primarily used as a building block in organic synthesis, particularly for Suzuki-Miyaura cross-coupling reactions to introduce the 3-pyridyl moiety into complex molecules for pharmaceutical and agrochemical research.
What are the CAS number and chemical formula for 3-Pyridineboronic acid MIDA ester?
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The CAS number is 1257740-56-9, and the chemical formula is C10H11BN2O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product for research and chemical synthesis purposes. The specific grade and purity are typically detailed on the Certificate of Analysis. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated.
How should 3-Pyridineboronic acid MIDA ester be handled safely?
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Based on GHS classifications, 3-Pyridineboronic acid MIDA ester is an irritant to skin, eyes, and the respiratory system (H315, H319, H335). Handle with appropriate personal protective equipment, including a dust mask (type N95 or equivalent), eyeshields, and gloves, in a well-ventilated area. Avoid breathing dust.
How is this chemical typically packed and shipped?
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This chemical is carefully packed to ensure stability during transit and is available for global export by Tech Serve Solutions, adhering to all relevant shipping regulations.
How can I request a sample or quote for 3-Pyridineboronic acid MIDA ester?
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To request a sample or a quote, please contact our sales team through the website or by email, providing your contact details and the required quantity.
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