N-Methyl-2-(tributylstannyl)indole
N-Methyl-2-(tributylstannyl)indole (CAS: 157427-46-8), with the molecular formula C21H35NSn and a molecular weight of 420.22 g/mol, is an organotin compound. It serves as a valuable reagent in organic synthesis, particularly for introducing the N-methylindole moiety into complex molecules. Its applications leverage the reactivity of the carbon-tin bond for cross-coupling reactions, facilitating the construction of sophisticated chemical structures.

Organometallic Reagent in Synthesis
This compound functions as an organometallic reagent, enabling the formation of new carbon-carbon bonds through various cross-coupling reactions. It is particularly useful for the stannylation of indoles, a key step in the synthesis of complex organic molecules.
Intermediate for Pharmaceutical Synthesis
N-Methyl-2-(tributylstannyl)indole can act as an intermediate in the development of novel pharmaceutical compounds. Its indole core is a common structural motif in many biologically active molecules, and the tributylstannyl group allows for its facile incorporation into drug candidates.
Research Chemical
Utilised in academic and industrial research laboratories for exploring new synthetic methodologies and for the creation of custom organic compounds. Its specific reactivity profile makes it an interesting tool for synthetic chemists.
| Molecular weight | 420.22 |
|---|---|
| Empirical formula | C21H35NSn |
| Assay | 97% |
| Density | 1.140 g/mL at 25 °C |
| Storage temperature | 2-8°C |
| Flash point | >149 °C / >300.2 °F |
|---|---|
| Transport (UN / ADR) | UN 2788 6.1 / PGIII |
| Water hazard class (WGK, DE) | 1 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-Methyl-2-(tributylstannyl)indole used for?
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N-Methyl-2-(tributylstannyl)indole is primarily used as an organometallic reagent in organic synthesis for introducing the N-methylindole moiety into target molecules, often serving as an intermediate in pharmaceutical research and development.
What is the CAS number and molecular formula?
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The CAS number for N-Methyl-2-(tributylstannyl)indole is 157427-46-8, and its molecular formula is C21H35NSn.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N-Methyl-2-(tributylstannyl)indole with a minimum assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should N-Methyl-2-(tributylstannyl)indole be handled and stored?
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This compound is classified under UN 2788, Hazard Class 6.1, Packing Group III, and has a flash point above 149 °C (299 °F). It should be stored at refrigeration temperatures between 2-8°C. Always consult the Safety Data Sheet (SDS) for comprehensive handling and safety information.
How can I request a quote or sample?
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To request a quote or a sample, please contact our sales department through the website or by phone. Our team will be happy to assist you with your inquiry.
Is this product suitable for food or pharmaceutical manufacturing?
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Based on the available data, this product is supplied at 97% purity and is not designated as USP, BP, or EP grade, indicating it is intended for research and chemical synthesis purposes, not for direct use in food or pharmaceutical manufacturing without further purification and validation.
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