3-Fluoro-1,2-propanediol
3-Fluoro-1,2-propanediol (CAS 453-16-7), with the linear formula FCH₂CH(OH)CH₂OH and a molecular weight of 94.08 g/mol, is a fluorinated diol. It serves as a valuable intermediate in organic synthesis, particularly in the development of fluorinated compounds. Its structure makes it useful in biochemical research and as a building block for more complex molecules.
- IUPAC
- α-Fluorohydrin
- Synonyms
- FCH2CH(OH)CH2OH3-Fluoropropane-1,2-diolalpha-Fluorohydrin
Organic Synthesis Intermediate
3-Fluoro-1,2-propanediol is employed as a key intermediate in the synthesis of various organic compounds. Its fluorinated nature and diol functionality allow for versatile reactions in the construction of complex molecular architectures.
Biochemical Research
This compound finds application in biochemical research, potentially as a precursor for fluorinated analogues of biologically active molecules or as a tool in enzymatic studies.
Fluorinated Compound Development
It acts as a crucial building block for creating novel fluorinated compounds with potential applications in materials science and pharmaceuticals.
| Molecular weight | 94.08 |
|---|---|
| Linear formula | FCH2CH(OH)CH2OH |
| Boiling point | 102-103 °C/13 mmHg(lit.) |
| Density | 1.1 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.422(lit.) |
| Storage temperature | 2-8°C |
Hazard statements
- H301Toxic if swallowed
- H311Toxic in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H331Toxic if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
- P311Call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Transport (UN / ADR) | UN 2810 6.1 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 23/24/25-36/37/38 |
| Safety statements (S) | 23-26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Fluoro-1,2-propanediol used for?
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3-Fluoro-1,2-propanediol is primarily used as an intermediate in organic synthesis and in biochemical research for the development of fluorinated compounds.
What is the CAS number and chemical formula for 3-Fluoro-1,2-propanediol?
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The CAS number is 453-16-7 and the linear chemical formula is FCH₂CH(OH)CH₂OH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Fluoro-1,2-propanediol typically as a research or technical grade chemical. The specific assay or purity available may vary; please contact us for detailed lot-specific information. We do not represent this product as USP, BP, or EP grade unless explicitly stated.
How should 3-Fluoro-1,2-propanediol be handled safely?
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3-Fluoro-1,2-propanediol is classified as Danger with hazards including acute toxicity (oral, dermal, inhalation) and skin/eye irritation. Handle with appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection (e.g., full-face respirator or type ABEK filter), in a well-ventilated area. Refer to the Safety Data Sheet for comprehensive guidance.
How is 3-Fluoro-1,2-propanediol packed and shipped?
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This chemical is packed according to UN 2810 regulations for toxic solids, liquids, or gases, Group II. Tech Serve Solutions exports globally, adhering to all relevant international shipping regulations for hazardous materials.
How can I request a sample or quote for 3-Fluoro-1,2-propanediol?
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To request a sample or a quote, please use the contact form on our website or email our sales department directly, specifying the product name and CAS number (453-16-7).
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