3-Chloropropionaldehyde diethylacetal
3-Chloropropionaldehyde diethyl acetal (CAS 35573-93-4) is an organic compound with the linear formula ClCH2CH2CH(OC2H5)2 and a molecular weight of 166.65 g/mol. This acetal serves as a valuable building block in organic synthesis, particularly in the preparation of various chemical intermediates. Its protected aldehyde functionality makes it useful for reactions where the aldehyde group needs to be masked during other transformations.
- IUPAC
- 3-Chloro-1,1-diethoxypropane
- Synonyms
- 3-Chloro-1,1-diethoxypropane

Organic Synthesis Intermediate
Utilised as a versatile building block in the synthesis of more complex organic molecules. Its acetal group provides protection for the aldehyde functionality, allowing for selective reactions elsewhere in the molecule.
Pharmaceutical Intermediate Production
Serves as a precursor in the development pathways for active pharmaceutical ingredients (APIs). Its structure lends itself to incorporation into various drug discovery and development programmes.
Specialty Chemical Manufacturing
Employed in the manufacture of specialty chemicals where a 3-carbon chain with masked aldehyde and terminal chlorine is required.
| Molecular weight | 166.65 |
|---|---|
| Linear formula | ClCH2CH2CH(OC2H5)2 |
| Assay | ≥90% (GC) |
| Boiling point | 84 °C/25 mmHg(lit.) |
| Density | 0.995 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.42(lit.)n20/D 1.420 |
| Storage temperature | 2-8°C |
| Contains / stabiliser | ~0.5% CaCO3 as stabilizer |


Hazard statements
- H226Flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 54 °C / 129.2 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 10-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Chloropropionaldehyde diethyl acetal used for?
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3-Chloropropionaldehyde diethyl acetal is primarily used as a building block in organic synthesis and as an intermediate in the production of pharmaceuticals and specialty chemicals. Its acetal group serves as a protected aldehyde.
What is the CAS number and chemical formula for 3-Chloropropionaldehyde diethyl acetal?
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The CAS number is 35573-93-4 and the linear chemical formula is ClCH2CH2CH(OC2H5)2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Chloropropionaldehyde diethyl acetal with an assay of ≥90% (GC). We do not represent this product as USP, BP, or EP grade.
How should 3-Chloropropionaldehyde diethyl acetal be handled safely?
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3-Chloropropionaldehyde diethyl acetal is a flammable liquid and vapour (H226) and causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Always use with appropriate personal protective equipment, including eyeshields, chemical-resistant gloves, and ensure adequate ventilation. Store in a cool, well-ventilated area away from ignition sources, and keep at 2-8°C.
Is 3-Chloropropionaldehyde diethyl acetal a controlled substance?
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Based on the provided data, 3-Chloropropionaldehyde diethyl acetal is not listed as a controlled substance.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions handles packing and shipping in accordance with international regulations for hazardous materials. We are experienced global exporters of fine chemicals, pharmaceutical intermediates, and laboratory reagents.
How can I request a sample or quote for 3-Chloropropionaldehyde diethyl acetal?
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To request a sample or a quote, please contact our sales department through the website or by phone, providing the product name and CAS number (35573-93-4).
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