3-Chloropropanesulfonyl chloride
3-Chloropropanesulfonyl chloride (CAS: 1633-82-5, Formula: Cl(CH2)3SO2Cl, MW: 177.05) is a reactive organic building block. As a difunctional sulfonyl halide, it is primarily employed in chemical synthesis for the preparation of various heterocyclic compounds and sulfur-containing molecules. Its specific applications include the synthesis of cyclic urea, oxazolidinone, and sulfonamide analogues, as well as propanesultam. This compound serves as a valuable intermediate for researchers and manufacturers in the pharmaceutical and chemical industries.
Synthesis of Heterocyclic Compounds
3-Chloropropanesulfonyl chloride is utilized in the preparation of cyclic urea, oxazolidinone, and sulfonamide analogues. These structures are foundational in medicinal chemistry and materials science.
Preparation of Propanesultam
This compound serves as a direct precursor for the synthesis of propanesultam, a cyclic sulfonamide. Propanesultam is a significant intermediate in organic synthesis.
General Organic Synthesis
As a versatile sulfonyl halide, 3-Chloropropanesulfonyl chloride acts as a key building block for introducing the 3-chloropropanesulfonyl group into various organic molecules, facilitating the construction of complex structures.
| Molecular weight | 177.05 |
|---|---|
| Linear formula | Cl(CH2)3SO2Cl |
| Assay | ≥98.0% (AT) |
| Boiling point | 70 °C/0.5 mmHg(lit.) |
| Density | 1.456 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.489(lit.)n20/D 1.491 |
| Application | 3-Chloropropanesulfonyl chloride has been used in the preparation of:• cyclic urea, oxazolidinone and sulfonamide analogs1• propanesultam2 |
Hazard statements
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 110 °C / 230 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34-36/37 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Chloropropanesulfonyl chloride used for?
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3-Chloropropanesulfonyl chloride is used as a building block in chemical synthesis, notably for preparing cyclic urea, oxazolidinone, sulfonamide analogues, and propanesultam.
What are the CAS number and chemical formula for 3-Chloropropanesulfonyl chloride?
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The CAS number is 1633-82-5 and the chemical formula is Cl(CH2)3SO2Cl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Chloropropanesulfonyl chloride with an assay of ≥98.0% (AT). This product is not represented as USP, BP, EP, or other pharmacopoeia grades.
How should 3-Chloropropanesulfonyl chloride be handled safely?
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3-Chloropropanesulfonyl chloride is a corrosive substance that can cause severe skin burns and eye damage, and may cause respiratory irritation. Handle with appropriate personal protective equipment, including chemical-resistant gloves, eye protection (goggles and face shield), and respiratory protection. Ensure adequate ventilation. Refer to the Safety Data Sheet (SDS) for comprehensive safety information.
Does Tech Serve Solutions export 3-Chloropropanesulfonyl chloride?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 3-Chloropropanesulfonyl chloride.
How can I request a sample or a quote for 3-Chloropropanesulfonyl chloride?
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Please contact our sales team via the website or by phone to request a sample or a quotation for 3-Chloropropanesulfonyl chloride.
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