3-Chloro-4-methylphenylboronic acid
3-Chloro-4-methylphenylboronic acid (CAS: 175883-63-3), with a molecular formula of C7H8BClO2 and a molecular weight of 170.40 g/mol, is a valuable aryl boronic acid derivative. This compound serves as a key reactant in various organic syntheses, including the preparation of fluorenes, biaryl amides with potential muscarinic activity, and TRPV1 antagonists. It is an essential building block for advanced chemical research and development.
Synthesis of Fluorenes
This boronic acid is utilised as a reactant in intramolecular aromatic carbenoid insertion reactions, a crucial step in synthesising complex fluorene structures.
Biaryl Amide Synthesis
It participates in the synthesis of biaryl amides exhibiting muscarinic acetylcholine receptor subtype M1 agonistic activity, contributing to medicinal chemistry research.
TRPV1 Antagonist Preparation
Used in the preparation of TRPV1 antagonists, which are investigated as potential treatments for chronic pain conditions.
Borinic Acid Ester Synthesis
Facilitates the preparation of borinic acid picolinate esters, with applications in the treatment of cutaneous diseases.
| Molecular weight | 170.40 |
|---|---|
| Empirical formula | C7H8BClO2 |
| Application | Reactant involved in: • Intromolecular aromatic carbenoid insertion for the synthesis of fluorenes1• Synthesis of biaryl amides with muscarinic acetylcholine receptor subtype M1 agonistic activity2• Preparation of borinic acid picolinate esters for use against cutaneous diseases3• Synthesis of TRPV1 antagonists as treatment for chronic pain4 |
| Melting point | 228-232 °C |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Chloro-4-methylphenylboronic acid used for?
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3-Chloro-4-methylphenylboronic acid is used as a reactant in organic synthesis for preparing fluorenes, biaryl amides with muscarinic activity, borinic acid picolinate esters for cutaneous diseases, and TRPV1 antagonists for pain treatment.
What are the CAS number and formula for 3-Chloro-4-methylphenylboronic acid?
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The CAS number is 175883-63-3, and the empirical formula is C7H8BClO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound for research and chemical synthesis purposes. The specific assay and grade information is available on the product's Certificate of Analysis. TSS does not represent this product as USP/BP/EP or for human consumption.
How should 3-Chloro-4-methylphenylboronic acid be handled?
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According to the safety data, this compound is classified with GHS hazards. Please consult the Safety Data Sheet (SDS) for detailed handling, storage, and personal protective equipment recommendations. It is classified under WGK Germany 3.
Does Tech Serve Solutions export 3-Chloro-4-methylphenylboronic acid?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals and laboratory reagents.
How can I request a sample or quote for 3-Chloro-4-methylphenylboronic acid?
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To request a sample or a quotation, please contact our sales team through the website or by telephone, referencing the product name and CAS number.
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