3,5-Diiodo-L-tyrosine dihydrate
3,5-Diiodo-L-tyrosine dihydrate (CAS: 18835-59-1), with the empirical formula C9H9I2NO3 · 2H2O and a molecular weight of 469.01 g/mol, is a crystalline white solid. This modified amino acid serves as a crucial substrate in the assay of halogenated tyrosine and thyroid hormone aminotransferase. It also acts as an intermediate in the biosynthesis and metabolic pathways of thyroid hormones, making it valuable in biochemical research and diagnostics.
- Synonyms
- C9H9I2NO3 · 2H2O

Enzyme Substrate
Utilised as a substrate for the enzymatic assay of halogenated tyrosine and thyroid hormone aminotransferase. Its specific structure facilitates the study of these enzyme activities.
Thyroid Hormone Metabolism Research
Serves as an intermediate in the biosynthesis and alternative metabolic pathways of thyroid hormones. This role is significant for researchers investigating endocrine system function.
Biochemical Reagent
A key biochemical reagent for studies involving modified amino acids and enzyme kinetics. Its inclusion in research protocols aids in understanding complex biological processes.
| Molecular weight | 469.01 |
|---|---|
| Empirical formula | C9H9I2NO3 · 2H2O |
| Form | crystalline |
| Colour | white |
| Storage temperature | −20°C |
| Application | Substrate for the assay of halogenated tyrosine and thyroid hormone aminotransferase.1,2 Intermediate in the biosynthesis and alternative pathways of metabolism of thyroid hormones.3 |
| Melting point | 200 °C (dec.)(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,5-Diiodo-L-tyrosine dihydrate used for?
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3,5-Diiodo-L-tyrosine dihydrate is primarily used as a substrate for the assay of halogenated tyrosine and thyroid hormone aminotransferase, and as an intermediate in the biosynthesis and metabolism of thyroid hormones.
What is the CAS number and formula for 3,5-Diiodo-L-tyrosine dihydrate?
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The CAS number is 18835-59-1, and the empirical formula is C9H9I2NO3 · 2H2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product as a crystalline white solid. The specific grade and purity are available upon request and are suitable for research and diagnostic applications. TSS does not represent this product as USP, BP, or EP grade.
How should 3,5-Diiodo-L-tyrosine dihydrate be handled safely?
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Handle with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves. Ensure adequate ventilation to avoid inhalation of dust, as it may cause respiratory irritation (H335). Avoid contact with skin (H315) and eyes (H319).
How is 3,5-Diiodo-L-tyrosine dihydrate shipped and exported?
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As a specialist global supplier and exporter since 1998, Tech Serve Solutions ensures secure and compliant packaging for domestic and international shipments of 3,5-Diiodo-L-tyrosine dihydrate.
How can I request a sample or quote for 3,5-Diiodo-L-tyrosine dihydrate?
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Please contact our sales department via the website or by phone to request a sample or a quotation for 3,5-Diiodo-L-tyrosine dihydrate.
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