3,5-Di-O-(p-toluyl)-2-deoxy-D-ribofuranosyl chloride
3,5-Di-O-(p-toluyl)-2-deoxy-D-ribofuranosyl chloride (CAS 4330-21-6) is a specialized chemical compound with the molecular formula C21H21ClO5 and a molecular weight of 388.84 g/mol. Supplied by Tech Serve Solutions with an approximate purity of 90%, this deoxyribose derivative serves as a key precursor in the synthesis of modified nucleosides and nucleotides, particularly those containing unnatural β-D-ribofuranosyl structures. It is typically stored at -20°C.
- Synonyms
- C21H21ClO5

Nucleoside and Nucleotide Synthesis
This compound is a valuable intermediate for the laboratory-scale synthesis of novel nucleosides and nucleotides. Its structure is specifically designed for incorporation into unnatural nucleotide analogues.
Biochemical Research
Utilised in biochemical research to explore the structure-activity relationships of nucleic acids and their components. It enables the creation of modified building blocks for further study.
Organic Synthesis Intermediate
Serves as a versatile building block in complex organic synthesis pathways, allowing chemists to introduce specific structural motifs into target molecules.
| Molecular weight | 388.84 |
|---|---|
| Empirical formula | C21H21ClO5 |
| Assay | ~90% |
| Storage temperature | −20°C |
| Application | 3,5-Di-O-(p-toluyl)-2-deoxy-D-ribofuranosyl is used as a precursor for the synthesis of unnatural β-D-ribofuranosyl containing nucleosides and nucleotides. |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,5-Di-O-(p-toluyl)-2-deoxy-D-ribofuranosyl chloride used for?
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It is used as a precursor for the synthesis of unnatural β-D-ribofuranosyl containing nucleosides and nucleotides.
What is the CAS number and chemical formula for this compound?
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The CAS number is 4330-21-6, and the empirical formula is C21H21ClO5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an approximate assay of 90%. We do not represent this product as USP, BP, or EP grade.
How should 3,5-Di-O-(p-toluyl)-2-deoxy-D-ribofuranosyl chloride be handled?
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Handle with appropriate personal protective equipment, including a dust mask (NIOSH type N95 recommended), eyeshields, and gloves. Avoid breathing dust. Ensure adequate ventilation. Refer to the Safety Data Sheet for comprehensive handling information.
Is this chemical a controlled substance?
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Based on the provided data, there is no indication that this compound is a controlled substance.
How is this chemical typically packed and exported?
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This chemical is typically stored at -20°C. As a global supplier, Tech Serve Solutions adheres to all relevant regulations for packing and exporting fine chemicals worldwide.
How can I request a sample or quote for 3,5-Di-O-(p-toluyl)-2-deoxy-D-ribofuranosyl chloride?
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Please contact our sales team directly via the website or email to request a sample or a formal quotation. Our specialists will assist you promptly.
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