3,4-Dichloroisocoumarin
3,4-Dichloroisocoumarin (CAS: 51050-59-0) is a halogenated organic compound with the molecular formula C9H4Cl2O2 and a molecular weight of 215.03 g/mol. This chemical is a useful reagent in biological research, particularly in staining methods for macrophage identification. It serves as a valuable tool in cell biology studies for researchers investigating cellular processes and enzyme activity.
- IUPAC
- 3,4-Dichloro-2-benzopyran-1-one,3,4-DCI
- Synonyms
- C9H4Cl2O23,4-Dichloro-2-benzopyran-1-one3,4-DCI
Macrophage Identification
3,4-Dichloroisocoumarin is employed in a rapid staining method for the identification of macrophages. Counts obtained via this method have been validated against complex morphological criteria, phagocytosis assays, and the presence of Fc receptors.
Cell Biology Research
As a bioactive small molecule, this compound finds application in cell biology. It is relevant to studies involving apoptosis enzymes and cell signaling pathways, contributing to a deeper understanding of cellular functions.
Enzyme Inhibition Studies
The compound can be utilised in research related to broad-spectrum inhibitors of proteolytic enzyme classes, including cathepsin G and elastase, leucocyte.
| Molecular weight | 215.03 |
|---|---|
| Empirical formula | C9H4Cl2O2 |
| Storage temperature | 2-8°C |
| Application | Useful in a rapid staining method for identification of macrophages; counts by this method were confirmed by the more complex morphological criteria, by phagocytosis, and by the presence of Fc receptors.1 |
Hazard statements
- H301Toxic if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,4-Dichloroisocoumarin used for?
+
3,4-Dichloroisocoumarin is primarily used in a rapid staining method for the identification of macrophages in biological research. It also serves as a tool in cell biology studies investigating apoptosis enzymes and cell signaling, and in research concerning inhibitors of proteolytic enzymes.
What is the CAS number and formula for 3,4-Dichloroisocoumarin?
+
The CAS number for 3,4-Dichloroisocoumarin is 51050-59-0, and its empirical formula is C9H4Cl2O2.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 3,4-Dichloroisocoumarin for research purposes. The specific assay and purity are detailed in the product specifications. TSS does not represent this product as USP, BP, EP, or for pharmaceutical, nutraceutical, or food use.
How should 3,4-Dichloroisocoumarin be handled safely?
+
Handling 3,4-Dichloroisocoumarin requires strict safety precautions due to its toxic and irritant nature. Use appropriate personal protective equipment, including eyeshields, faceshields, gloves, and a P2 respirator. Ensure adequate ventilation and avoid inhalation, skin, and eye contact. Refer to the safety data sheet for comprehensive guidance.
How is 3,4-Dichloroisocoumarin packed, shipped, and exported?
+
3,4-Dichloroisocoumarin is carefully packed to maintain stability and prevent damage during transit. As a global supplier, Tech Serve Solutions has extensive experience in exporting chemicals, adhering to all relevant international shipping regulations for hazardous materials such as UN 2811.
How can I request a sample or quote for 3,4-Dichloroisocoumarin?
+
To request a sample or a quotation for 3,4-Dichloroisocoumarin, please contact the Tech Serve Solutions sales team via the website or direct inquiry. Provide your specific requirements and shipping details.
▶ Related products
![(±)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide (C8H13N3O4) — chemical structure, CAS 138472-01-2; Biochemicals & Reagents, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F138472-01-2.png&w=3840&q=75)
(±)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide
C8H13N3O4
Biochemicals & Reagents![(±)-(E)-4-Ethyl-2-[(Z)-hydroxyimino]-5-nitro-3-hexen-1-yl-nicotinamide (C14H18N4O4) — chemical structure, CAS 162626-99-5; Biochemicals & Reagents, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F162626-99-5.png&w=3840&q=75)
(±)-(E)-4-Ethyl-2-[(Z)-hydroxyimino]-5-nitro-3-hexen-1-yl-nicotinamide
C14H18N4O4
Biochemicals & Reagents
(±)-2,5-Dimethoxy-4-bromoamphetamine hydrobromide
Biochemicals & Reagents
(±)-2-(p-Methoxyphenoxy)propionic acid
C10H12O4
Biochemicals & Reagents
(±)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene hydrobromide
C10H13NO2·HBr
Biochemicals & Reagents
(±)-2-Hydroxydecanoic acid
C10H20O3
Biochemicals & Reagents
(±)-3-Hydroxydecanoic acid
C10H20O3
Biochemicals & Reagents
(±)-3-Hydroxyoctanoic acid
C8H16O3
Biochemicals & Reagents▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis