3,3′-Dipropylthiadicarbocyanine iodide
3,3′-Dipropylthiadicarbocyanine iodide (CAS 53213-94-8) is a lipophilic fluorescent probe with a molecular weight of 546.53 g/mol. This compound is primarily employed in biological research for its ability to indicate changes in cellular membrane potential and configuration. It serves as a valuable tool for detecting the effects of various membrane-interacting agents in scientific investigations.
- IUPAC
- 3-Propyl-2-[5-[3-propyl-2(3H)-benzothiazolylidene]-1,3-pentadienyl]benzothiazolium iodide,DiSC3(5)
- Synonyms
- 3-Propyl-2-[5-[3-propyl-2(3H)-benzothiazolylidene]-1,3-pentadienyl]benzothiazolium iodideDiSC3(5)
Transmembrane Potential Studies
Utilised as a fluorogenic probe to detect and quantify alterations in transmembrane potential induced by different membrane-active agents. Its lipophilic nature allows it to integrate into cell membranes, providing a measurable fluorescent signal responsive to potential changes.
Membrane Configuration Analysis
Employed to study changes in membrane structure or configuration. The probe's fluorescence characteristics can shift in response to alterations in the lipid bilayer, making it useful for assessing the impact of various compounds on membrane organisation.
Biochemical Assays
A useful reagent in various biochemical assays requiring fluorescent detection of membrane activity. It is suitable for fluorescence applications and can be dissolved in DMF for experimental use.
| Molecular weight | 546.53 |
|---|---|
| Empirical formula | C25H27IN2S2 |
| Assay | ≥98.0% (TLC) |
| Solubility | DMF: soluble |
| Application | 3,3′-Dipropylthiadicarbocyanine iodide [DiSC3(5)] is used as a fluorogenic probe to detect and measure changes in transmembrane potential or configuration induced by membrane altering agents. |
| Suitability | suitable for fluorescence |
| Melting point | 245 °C (dec.)(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Fluorescence | λex 500 nm; λem 705 nm in DMF |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,3′-Dipropylthiadicarbocyanine iodide used for?
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3,3′-Dipropylthiadicarbocyanine iodide is used as a fluorogenic probe to detect and measure changes in transmembrane potential or configuration induced by membrane-altering agents.
What are the CAS number and formula for 3,3′-Dipropylthiadicarbocyanine iodide?
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The CAS number is 53213-94-8 and the empirical formula is C25H27IN2S2. The molecular weight is 546.53 g/mol.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3,3′-Dipropylthiadicarbocyanine iodide with a purity of ≥98.0% (TLC). This product is suitable for research purposes and is not represented as USP, BP, EP, or pharmacopoeia grade.
What are the safety and handling considerations for this chemical?
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This compound is classified as a Warning with hazard statements H315, H319, and H335, indicating it causes skin irritation, serious eye irritation, and may cause respiratory irritation. Recommended personal protective equipment includes a dust mask (type N95 US), eyeshields, and gloves. Handle in a well-ventilated area.
How is this product packed, shipped, and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. Products are carefully packed according to international shipping regulations to ensure safe transit. Please contact us for specific export details.
How can I request a sample or quote?
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To request a sample or a quote for 3,3′-Dipropylthiadicarbocyanine iodide, please visit the Tech Serve Solutions website or contact our sales department directly through the provided channels.
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