3,4-(Methylenedioxy)phenylmagnesium bromide solution
3,4-(Methylenedioxy)phenylmagnesium bromide solution (CAS 17680-04-5) is an organometallic reagent with a molecular weight of 225.32 g/mol. Supplied as a 1.0 M solution in THF:toluene (1:1), this aryl Grignard reagent is a valuable intermediate in organic synthesis. It is primarily employed for introducing the 3,4-(methylenedioxy)phenyl moiety into various organic molecules, facilitating the construction of complex structures in pharmaceutical and fine chemical research.
- Synonyms
- C7H5BrMgO2
Organometallic Synthesis
As a Grignard reagent, it readily reacts with electrophiles such as aldehydes, ketones, esters, and epoxides. This reactivity enables the formation of new carbon-carbon bonds, crucial for building molecular complexity in the synthesis of target compounds.
Pharmaceutical Intermediate
The 3,4-(methylenedioxy)phenyl group is a substructure found in various biologically active molecules. This reagent serves as a key building block for accessing such pharmaceutical intermediates and potential drug candidates.
Fine Chemical Production
It is utilised in the synthesis of specialized fine chemicals where the methylenedioxyphenyl functionality is a required structural element. Its application spans research and development through to pilot-scale production.
| Molecular weight | 225.32 |
|---|---|
| Empirical formula | C7H5BrMgO2 |
| Density | 1.04 g/mL at 25 °C |
| Concentration | 1.0 M in THF: toluene (1:1) |
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Flash point | -10 °C / 14 °F |
|---|---|
| Transport (UN / ADR) | UN 2924 3/PG 2 |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 11-34-48/20-63-65-67 |
| Safety statements (S) | 26-36/37/39-45-62 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,4-(Methylenedioxy)phenylmagnesium bromide solution used for?
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3,4-(Methylenedioxy)phenylmagnesium bromide solution is a versatile Grignard reagent used primarily for introducing the 3,4-(methylenedioxy)phenyl group in organic synthesis, serving as an intermediate for pharmaceutical and fine chemical production.
What is the CAS number and formula for 3,4-(Methylenedioxy)phenylmagnesium bromide solution?
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The CAS number is 17680-04-5 and the empirical formula is C7H5BrMgO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound as a 1.0 M solution in THF:toluene (1:1). It is suitable for research and chemical synthesis purposes. We do not represent this product as USP, BP, or EP grade.
How should 3,4-(Methylenedioxy)phenylmagnesium bromide solution be handled?
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This is a highly flammable liquid and vapour, and causes severe skin burns and eye damage. It may also cause respiratory irritation and has potential for teratogenic effects. Handle with appropriate personal protective equipment in a well-ventilated area, away from ignition sources.
How is 3,4-(Methylenedioxy)phenylmagnesium bromide solution packed, shipped, and exported?
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This reagent is supplied in specialised packaging suitable for hazardous and flammable liquids, adhering to international shipping regulations. TSS is experienced in global export of such chemicals.
How can I request a sample or quote for 3,4-(Methylenedioxy)phenylmagnesium bromide solution?
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Please contact our sales team via the website or email to request a sample or a formal quotation for 3,4-(Methylenedioxy)phenylmagnesium bromide solution.
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