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3,4-(Methylenedioxy)toluene

CAS 7145-99-5C8H8O2Chemical Synthesis

3,4-(Methylenedioxy)toluene (CAS: 7145-99-5), also known as 5-Methyl-1,3-benzodioxole, is an organic compound with the molecular formula C8H8O2 and a molecular weight of 136.15 g/mol. This chemical serves as a valuable building block in organic synthesis. It has been employed as a cation scavenger for the selective cleavage of 4-(3,4-dimethoxyphenyl)benzyl ethers, yielding deprotected products. Tech Serve Solutions supplies this compound for research and chemical synthesis applications.

IUPAC
5-Methyl-1,3-benzodioxole
Synonyms
5-Methyl-1,3-benzodioxole
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3,4-(Methylenedioxy)toluene (C8H8O2) — chemical structure, CAS 7145-99-5; Chemistry, fine chemical supplied by Tech Serve Solutions
Building BlocksChemical SynthesisOrganic Building BlocksOxygen CompoundsProtected Alcohols/Phenols
01 /Applications

Cation Scavenger in Organic Synthesis

3,4-(Methylenedioxy)toluene functions as a cation scavenger. It is specifically utilised for the selective cleavage of 4-(3,4-dimethoxyphenyl)benzyl (DMPBn) ethers, facilitating the deprotection process.

Organic Building Block

This compound is classified as an organic building block, making it a useful intermediate in the synthesis of more complex molecules. Its structure lends itself to various chemical transformations.

Research and Development

As a fine chemical, 3,4-(Methylenedioxy)toluene is suitable for use in research laboratories. It supports the development of new synthetic routes and the investigation of novel chemical entities.

02 /Properties
Molecular weight136.15
Empirical formulaC8H8O2
Assay97%
Boiling point199-200 °C(lit.)
Density1.135 g/mL at 25 °C(lit.)
Refractive indexn20/D 1.532(lit.)
Application3,4-(Methylenedioxy)toluene was used as a cation scavenger for the selective cleavage of the 4-(3,4-dimethoxyphenyl)benzyl (DMPBn) ethers affording the corresponding deprotected products1.
03 /Safety & handling
GHS hazard pictogram: Corrosive (GHS05)
Corrosive
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Danger

Hazard statements

  • H302Harmful if swallowed
  • H318Causes serious eye damage

Precautionary statements

  • P280Wear protective gloves, clothing and eye/face protection
  • P305IF IN EYES
Protective equipmentEyeshields, Gloves, half-mask respirator (EU), half-mask respirator (US), multi-purpose combination respirator cartridge (US)
Flash point76 °C / 168.8 °F
Water hazard class (WGK, DE)3
Hazard codes (EU)Xn
Risk statements (R)22-41
Safety statements (S)26-39

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
7145-99-5
MDL number
MFCD00005833
PubChem substance
24857165
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 3,4-(Methylenedioxy)toluene used for?

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3,4-(Methylenedioxy)toluene is used as a cation scavenger in organic synthesis for the selective cleavage of certain ethers and as a general organic building block in chemical research and development.

What is the CAS number and formula for 3,4-(Methylenedioxy)toluene?

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The CAS number for 3,4-(Methylenedioxy)toluene is 7145-99-5, and its molecular formula is C8H8O2.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies 3,4-(Methylenedioxy)toluene with an assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.

How should 3,4-(Methylenedioxy)toluene be handled safely?

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3,4-(Methylenedioxy)toluene is a Danger signal word substance, harmful if swallowed (H302) and causes serious eye damage (H318). Appropriate personal protective equipment including eyeshields, gloves, and respiratory protection should be used. Ensure good ventilation and avoid contact with eyes, skin, and clothing.

Can Tech Serve Solutions export 3,4-(Methylenedioxy)toluene?

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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 3,4-(Methylenedioxy)toluene. We can cater to international shipping requirements.

How can I request a sample or quote for 3,4-(Methylenedioxy)toluene?

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To request a sample or a quote for 3,4-(Methylenedioxy)toluene, please contact our sales team through the website or by phone, providing your specific requirements.

Need 3,4-(Methylenedioxy)toluene in a specific grade or volume?