3,4-(Methylenedioxy)phenylboronic acid
3,4-(Methylenedioxy)phenylboronic acid (CAS: 94839-07-3) is a valuable organoboronic acid with the molecular formula C7H7BO4 and a molecular weight of 165.94 g/mol. It serves as a key reactant in various synthetic organic chemistry applications, including Petasis reactions, Mannich-type multicomponent assemblies, Suzuki-Miyaura cross-couplings, and oxidative Heck reactions. This compound is essential for building complex molecular architectures in research and development.
- IUPAC
- 1,3-Benzodioxole-5-boronic acid
- Synonyms
- 1,3-Benzodioxole-5-boronic acid
Petasis Reaction
3,4-(Methylenedioxy)phenylboronic acid participates in the Petasis reaction, a multicomponent reaction involving glyoxylic acid, alpha-amino phosphonates, and organoboronic acids for the synthesis of diverse compounds.
Suzuki-Miyaura Cross-Coupling
This boronic acid is a suitable coupling partner in Suzuki-Miyaura cross-coupling reactions with aryl and heteroaryl halides, enabling the formation of new carbon-carbon bonds.
Mannich-Type Reactions
It is employed in Mannich-type multicomponent assemblies and 1,3-dipolar cycloadditions, leading to the synthesis of tetrahydroisoquinoline fused isoxazolidine scaffolds.
Oxidative Heck Reaction
The compound can be utilized in oxidative Heck reactions for the efficient synthesis of functionalised cinnamaldehyde derivatives.
| Molecular weight | 165.94 |
|---|---|
| Empirical formula | C7H7BO4 |
| Application | Reactant involved in:• Petasis reaction between glyoxylic acid, α-amino phosphonates, and organylboronic acids1• Mannich-type multicomponent assembly and 1,3-dipolar cycloaddition for synthesis of tetrahydroisoquinoline fused isoxazolidine scafford2• Suzuki-Miyaura cross-coupling of aryl and heteroaryl halides3,4• Oxidative Heck reaction for synthesis of functionalized cinnamaldehyde derivatives5• Intramolecular Alder-ene and Pictet-Spengler reactions for synthesis of crinine6 |
| Melting point | 224-229 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,4-(Methylenedioxy)phenylboronic acid used for?
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3,4-(Methylenedioxy)phenylboronic acid is used as a reactant in organic synthesis, including Petasis reactions, Mannich-type assemblies, Suzuki-Miyaura cross-couplings, and oxidative Heck reactions.
What are the CAS number and formula for 3,4-(Methylenedioxy)phenylboronic acid?
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The CAS number is 94839-07-3 and the empirical formula (Hill notation) is C7H7BO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3,4-(Methylenedioxy)phenylboronic acid for research and development purposes. The specific grade and purity are available upon request. We do not represent this product as USP, BP, or EP grade.
What are the safety and handling precautions for this compound?
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This compound requires the use of eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Consult the Safety Data Sheet for comprehensive handling information.
How is 3,4-(Methylenedioxy)phenylboronic acid packaged and shipped?
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3,4-(Methylenedioxy)phenylboronic acid is carefully packaged to ensure safe transit and is exported globally by Tech Serve Solutions.
How can I request a sample or quote for 3,4-(Methylenedioxy)phenylboronic acid?
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To request a sample or a quotation for 3,4-(Methylenedioxy)phenylboronic acid, please contact the Tech Serve Solutions sales team through our website or by phone.
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